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Model output · Signal date 2026-10-14

Sionna Therapeutics, Inc. (SION) Stock Forecast Oct. 14, 2026

Analysis updated on Oct. 14, 2026 (UTC) · Total · absolute moveSwitch to Alpha · Nasdaq

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Rating · 90D ▲ Bullish Exact rating locked
90-day forecast Sign up free to reveal
30-day forecast Total
Rank in coverage Top 35% of 5379 stocks scored
Rank correlation · 90D n/a No per-ticker sample yet
Market Cap $198M small-cap · #60 of 60 peers
Summary

Sionna Therapeutics, Inc. (SION) stock forecast summary

Our AI ranks Sionna Therapeutics, Inc. outside the neutral middle of its coverage (a directional signal). Create a free account and follow it to see the exact price target.

Sionna Therapeutics, Inc. is a small-cap company with a market capitalization of $198M. It ranks number 60 by market capitalization among the 60 Pharmaceutical Preparations issuers in our coverage with a current forecast.

A per-ticker accuracy statistic for SION is published only once its sample size is known. Across our coverage, the out-of-sample test on 4537 stocks from 2025-01-06 to 2026-06-09 produced a positive net return in 73.7% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

Expected absolute price move over the horizon, market included. This is the number a price target is built from. Ratings: strong buy ≥ +4.5%, buy ≥ +3.4%, sell < +2.1%, strong sell < +0.9% (top 15%, next 20%, middle 30%, next 20%, bottom 15% of the 2026-10-13 signals)

A free account shows the exact forecast, rating and rank of 3 tickers you follow, SION included.

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Price

SION price chart and AI forecast

SION
Cross-section · 2026-10-13

How SION ranks among 5379 stocks

90D Total forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).

Fundamentals

Sionna Therapeutics, Inc. (SION) fundamentals

Trailing twelve months. The industry median and the rank (1 = highest) are taken over the Pharmaceutical Preparations peers listed below that report each metric.

Financial statement data is not available for this company: its filings are not in a form the pipeline converts, so only market data is shown.

Reported net income does not reconcile with earnings per share and the share count, so net-income-based ratios are withheld.

Valuation & Market

MetricSIONIndustry medianRank
Market Cap $198M $12.02B 60/60

Profitability & Margins

MetricSIONIndustry medianRank
ROIC -40.2% -6.2% 31/41

Financial Health

MetricSIONIndustry medianRank
Current Ratio 20.05x 3.37x 7/50
D/E Ratio 0.07x 0.85x 36/43
Financial Leverage 1.07x 1.85x 36/43

Dividend & Shareholder Information

MetricSIONIndustry medianRank
Shares Outstanding 45M – –
Quarterly Financial Reports

SION quarterly financials and insider trading

Industry Peers · Pharmaceutical Preparations

Sionna Therapeutics, Inc. (SION) industry peers

Companies classified under the same SEC industry code as Sionna Therapeutics, Inc. (Pharmaceutical Preparations): 60 common-stock issuers with a forecast this week, one row per issuer, largest first. This is a classification match, not a curated list of competitors.

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Company 90-Day AI Forecast (Total) Market Cap P/E Ratio P/B Ratio
SION Sionna Therapeutics, Inc. ▲ $198M – –
LLY Eli Lilly & Co ▶ $1.10T 41.1x 111.7x
JNJ Johnson & Johnson ▼ $599.12B 28.5x 7.1x
ONC Beone Medicines Ltd. ▶ $515.98B – 99.7x
ABBV Abbvie Inc. ▼ $484.61B 76.8x –
MRK Merck & Co., Inc. ▼ $350.29B 110.4x 8.4x
NVS Novartis Ag ▼ $271.74B – –
GSK Gsk Plc ▼ $199.68B – –
ABT Abbott Laboratories ▼ $178.73B 28.6x 3.5x
PFE Pfizer Inc ▶ $161.70B 37.3x 1.9x
VRTX Vertex Pharmaceuticals Inc / Ma ▼ $122.98B 27.9x 6.1x
BMY Bristol Myers Squibb Co ▼ $115.76B 12.5x 5.2x
REGN Regeneron Pharmaceuticals, Inc. ▼ $77.54B 17.9x 2.5x
TEVA Teva Pharmaceutical Industries Ltd ▶ $48.07B 68.0x 6.2x
SNY Sanofi ▼ $47.70B – –
RPRX Royalty Pharma Plc ▶ $32.53B 39.9x 4.8x
ZTS Zoetis Inc. ▼ $30.70B 11.7x 9.8x
ALNY Alnylam Pharmaceuticals, Inc. ▼ $29.95B – 22.1x
TAK Takeda Pharmaceutical Co Ltd ▼ $29.46B – –
ATHE Alterity Therapeutics Ltd ▶ $26.01B – –
ZLAB Zai Lab Ltd ▶ $25.93B – 42.7x
ROIV Roivant Sciences Ltd. ▶ $24.09B – 5.7x
UTHR United Therapeutics Corp ▼ $23.31B 17.8x 3.6x
INSM Insmed Inc ▼ $21.14B – 27.9x
VTRS Viatris Inc ▶ $19.81B – –
ASND Ascendis Pharma A/S ▶ $13.83B – –
JAZZ Jazz Pharmaceuticals Plc ▼ $13.66B 14.5x 2.8x
CORT Corcept Therapeutics Inc ▲ $12.73B – 18.0x
SMMT Summit Therapeutics Inc. ▶ $12.38B – 19.7x
BBIO Bridgebio Pharma, Inc. ▲ $12.37B – –
KNSA Kiniksa Pharmaceuticals International, Plc ▲ $12.25B – 20.2x
HCM Hutchmed (China) Ltd ▶ $11.78B – 9.5x
ELAN Elanco Animal Health Inc ▲ $11.20B – 1.7x
RDY Dr Reddys Laboratories Ltd ▼ $10.66B – –
BMRN Biomarin Pharmaceutical Inc ▼ $10.53B – 1.7x
MDGL Madrigal Pharmaceuticals, Inc. ▶ $10.45B – 20.0x
PTGX Protagonist Therapeutics, Inc ▲ $8.96B – 10.7x
CYTK Cytokinetics Inc ▶ $8.57B – –
ARWR Arrowhead Pharmaceuticals, Inc. ▲ $8.21B – 17.6x
AXSM Axsome Therapeutics, Inc. ▼ $8.19B – 98.3x
SYRE Spyre Therapeutics, Inc. ▲ $7.09B – 6.4x
IONS Ionis Pharmaceuticals Inc ▶ $7.04B – 16.0x
ABVX Abivax S.A. ▼ $6.83B – –
PRAX Praxis Precision Medicines, Inc. ▲ $6.79B – 5.1x
ALKS Alkermes Plc. ▶ $6.67B – 3.7x
LEGN Legend Biotech Corp ▶ $6.61B – –
AMRX Amneal Pharmaceuticals, Inc. ▶ $6.25B – –
LGND Ligand Pharmaceuticals Inc ▼ $6.05B 30.7x 6.3x
BLTE Belite Bio, Inc ▲ $5.97B – 7.8x
RYTM Rhythm Pharmaceuticals, Inc. ▶ $5.96B – 57.9x
BLRX Biolinerx Ltd. ▼ $5.67B – –
MIRM Mirum Pharmaceuticals, Inc. ▲ $5.17B – –
ERAS Erasca, Inc. ▲ $5.17B – 14.3x
PTCT Ptc Therapeutics, Inc. ▶ $5.00B – –
TVTX Travere Therapeutics, Inc. ▲ $4.88B – 199.1x
COGT Cogent Biosciences, Inc. ▲ $4.87B – 9.2x
AMRN Amarin Corp Plc\Uk ▶ $4.86B – 11.0x
MANE Veradermics, Inc ▲ $4.86B – 6.0x
GPCR Structure Therapeutics Inc. ▲ $4.77B – 3.5x
DNTH Dianthus Therapeutics, Inc. /De/ ▲ $4.34B – 3.7x

Where SION sits on the market map

Life Sciences · Pharmaceutical Preparations
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News

Sionna Therapeutics, Inc. (SION) stock news

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FAQ

Sionna Therapeutics, Inc. (SION) stock forecast FAQ

What is the Sionna Therapeutics, Inc. (SION) stock forecast?

Our AI ranks Sionna Therapeutics, Inc. outside the neutral middle of its coverage (a directional signal). Create a free account and follow it to see the exact price target.

How accurate are Sionna Therapeutics, Inc. stock predictions?

A per-ticker accuracy statistic for SION is published only once its sample size is known. Across our coverage, the out-of-sample test on 4537 stocks from 2025-01-06 to 2026-06-09 produced a positive net return in 73.7% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

How often are Sionna Therapeutics, Inc. forecasts updated?

Sionna Therapeutics, Inc. forecasts are refreshed on trading days as the daily model run completes. The forecast on this page was produced on Oct. 14, 2026.

Which companies are Sionna Therapeutics, Inc.'s industry peers?

60 issuers in our coverage, SION included, share the SEC industry code Pharmaceutical Preparations. The largest are: Eli Lilly & Co (LLY), Johnson & Johnson (JNJ), Beone Medicines Ltd. (ONC), Abbvie Inc. (ABBV), Merck & Co., Inc. (MRK), Novartis Ag (NVS).

This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.