About the Company
Conivaptan, sold under the brand name Vaprisol, is a non-peptide inhibitor of the receptor for anti-diuretic hormone, also called vasopressin. It was approved in 2004 for hyponatremia (low blood sodium levels). The compound was discovered by Astellas and marked in 2006. The drug is now marketed by Cumberland Pharmaceuticals, Inc. Conivaptan inhibits two of the three subtypes of the vasopressin receptor (V1a and V2). Effectively, it causes iatrogenic nephrogenic diabetes insipidus. Conivaptan has not been approved by the American Food and Drug Administration for the treatment of decompensated congestive heart failure. However, in theory, vasopressin receptor antagonism would be particularly useful in this setting, and an initial study shows that it has some promise.
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Cumberland Pharmaceuticals Inc CPIX
We sell different types of products and services to both investment professionals and individual investors. These products and services are usually sold through license agreements or subscriptions ...
Cumberland County man charged with sexual abuse of juvenile female
Richard L. Ridley, 53, was previously arrested in February for violating Megan’s Law after running a carnival business in ...
2-alarm fire heavily damages Cumberland home
CUMBERLAND, R.I. (WPRI) — Four people evacuated their Cumberland home after a two-alarm fire broke out Monday morning. A ...
Neighbors report porch fire that spread to Cumberland home
Quick-thinking neighbors reported a porch fire that ended up spreading at a home in Cumberland Monday morning.
Four people displaced by Cumberland house fire
Fire crews responded at 6:27 a.m. to a Camp Street home in Cumberland for calls of a house fire that spread from the porch.
Correctional officer at Maryland state prison in Cumberland is stabbed by inmate Sunday evening
A correctional officer at a state prison in Cumberland was stabbed by an inmate Sunday evening.
Cumberland Police Department Announces Drug-Related Arrests
The Cumberland Police Department conducted several arrests related to controlled dangerous substances (CDS) on Wednesday, ...
See all homes sold in Cumberland County, April 15 to April 21
The following is a listing of all home transfers in Cumberland County reported from April 15 to April 21. There were 35 ...
Cumberland Woman Shot Fireworks At Victim Before Brawl
Jennifer Marie Carretti, 41, was arrested following an assault that involved the use of fireworks at a home on the 800 block ...
North Carolina man accused of traveling to Cumberland County for sex with minor
A North Carolina man is accused of traveling to Cumberland County to have sex with a minor. Brayan Garcia-Vazquez, 23, faces ...
10 most expensive homes sold in Cumberland County, April 15-21
A house in Hampden Township that sold for $1.3 million tops the list of the most expensive residential real estate sales in ...
Crash involving tractor-trailer in Cumberland County
Crews were called to the scene of a crash in Cumberland County Saturday morning. The crash, was on Interstate 81, and involved a tractor-trailer and an SUV, according to emergency dispatch. It ...
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