Acceleron Pharma, Inc. (NASDAQ:XLRN)

About the company

Acceleron Pharma, Inc. is a biopharmaceutical company, which engages in the discovery, development, and commercialization of therapeutics to treat serious and rare diseases. Its product candidates include Luspatercept, designed to patients with chronic anemia associated within a wide range of blood diseases; ACE-083, designed for the treatment of focal muscle disorders; and Sotatercept, designed to treat pulmonary arterial hypertension. The company was founded by John L. Knopf and Thomas P. Maniatis in June 2003 and is headquartered in Cambridge, MA.

Sector

Health Technology

Industry

Biotechnology

Employees

237

$76.00M

Total Revenue

237

Employees

$5B

Market Capitalization

-39.13

Price/Earning ratio

Stock price

Gross Margin (in %)

Total gross margin

$76M

Operating Margin (in %)

Total operating margin

$-148M

Net Margin (in %)

Total net margin

$-139M

Dividend Yield (in %)

Dividend per share

$0

Industry peers

Name Ticker Market capitalization (in USD Million) Revenues (in USD Million) Price/Book Price/Earning Net margin (in %)
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Audentes Therapeutics, Inc. BOLD 2638.68 None 7.17 -15.11 None
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Coherus BioSciences, Inc. CHRS 1372.50 435.00 8.24 9.15 33.42
Cortexyme, Inc. CRTX 1330.81 None 6.19 -27.81 None
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Heron Therapeutics, Inc. HRTX 1320.05 140.00 3.85 -6.84 -138.31
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Sangamo Therapeutics, Inc. SGMO 1117.08 107.00 3.44 -11.89 -89.31
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Meridian Bioscience, Inc. VIVO 1022.97 204.00 4.98 48.55 10.47
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BioXcel Therapeutics, Inc. BTAI 886.72 None 14.53 -22.20 None
Rhythm Pharmaceuticals, Inc. RYTM 858.00 None 3.83 -5.79 None
Myriad Genetics, Inc. MYGN 856.92 760.00 0.89 -5.79 -19.49
Atara Biotherapeutics, Inc. ATRA 807.40 None 3.42 -2.70 None
Morphic Holding, Inc. MORF 779.40 17.00 6.20 -14.35 -332.51
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CARA Therapeutics, Inc. CARA 770.88 24.00 5.11 -6.87 -480.29
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Replimune Group, Inc. REPL 753.44 None 4.44 -14.39 None
Precigen, Inc. PGEN 751.92 98.00 9.45 -2.36 -324.18
ImmunoGen, Inc. IMGN 746.64 87.00 -244.00 -8.56 -102.87
Kura Oncology, Inc. KURA 725.56 None 4.54 -10.57 None
Sinovac Biotech Ltd. SVA 711.70 246.00 1.82 15.78 16.18
Frequency Therapeutics, Inc. FREQ 702.15 36.00 4.26 -37.13 -52.16
Homology Medicines, Inc. FIXX 674.96 2.00 3.06 -5.88 None
Rapt Therapeutics, Inc. RAPT 673.20 1.00 5.18 -14.53 None
Dynavax Technologies Corp. DVAX 667.59 40.00 78.82 -4.84 -319.06
XBiotech, Inc. XBIT 667.46 13.00 1.21 0.99 None
Kadmon Holdings, Inc. KDMN 660.80 12.00 7.87 -6.84 -831.11
Radius Health, Inc. RDUS 651.82 191.00 -8.86 -5.13 -66.82
Vanda Pharmaceuticals, Inc. VNDA 651.75 237.00 1.55 5.56 49.12
BioCryst Pharmaceuticals, Inc. BCRX 637.54 48.00 251.00 -5.58 -241.66
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Molecular Templates, Inc. MTEM 540.40 19.00 7.38 -6.23 -439.47
Avrobio, Inc. AVRO 533.10 None 2.50 -6.56 None
UroGen Pharma Ltd. URGN 532.56 0.00 3.70 -4.37 -255.27
Stemline Therapeutics, Inc. STML 532.35 47.00 4.21 -7.63 -150.30
Corbus Pharmaceuticals Holdings, Inc. CRBP 524.70 36.00 25.65 -7.10 -207.87
Prevail Therapeutics, Inc. PRVL 523.60 None 3.55 -7.33 None
Syros Pharmaceuticals, Inc. SYRS 522.45 4.00 7.23 -6.83 None
Scholar Rock Holding Corp. SRRK 510.40 22.00 5.33 -8.76 -255.69
Flexion Therapeutics, Inc. FLXN 503.88 83.00 -9.75 -3.50 -175.76
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Rubius Therapeutics, Inc. RUBY 493.75 None 2.14 -2.77 None
Protagonist Therapeutics, Inc. PTGX 479.25 2.00 10.09 -5.69 -125.87
Voyager Therapeutics, Inc. VYGR 477.30 117.00 6.03 -12.17 -34.70
CEL-SCI Corp. CVM 473.55 0.00 42.28 -14.39 None
Syndax Pharmaceuticals, Inc. SNDX 466.56 2.00 9.85 -7.80 None
Neoleukin Therapeutics, Inc. NLTX 462.00 25.00 3.93 -5.26 -126.34
Personalis, Inc. PSNL 454.72 70.00 4.54 -15.62 -40.60
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MeiraGTx Holdings Plc MGTX 431.20 17.00 2.49 -8.44 -313.73
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Geron Corp. GERN 420.98 0.00 5.56 -5.56 -479.34
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Merus NV MRUS 411.32 29.00 4.01 -6.13 -225.72
Puma Biotechnology, Inc. PBYI 410.67 224.00 43.87 -4.97 -36.74
Unity Biotechnology, Inc. UBX 403.20 1.00 4.19 -4.41 None
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VBI Vaccines, Inc. VBIV 401.80 2.00 8.97 -7.97 None
MiMedx Group, Inc. MDXG 401.74 359.00 8.42 -13.54 -8.35
Harpoon Therapeutics, Inc. HARP 398.16 8.00 4.98 -7.72 -680.88
Clovis Oncology, Inc. CLVS 389.99 152.00 -4.59 -0.92 -271.12
CytomX Therapeutics, Inc. CTMX 386.86 78.00 5.53 -4.98 -97.82
Spectrum Pharmaceuticals, Inc. SPPI 380.73 109.00 2.60 -2.86 -109.77
Aspira Women's Health, Inc. AWH 372.60 5.00 81.00 -23.82 -307.31
Aptose Biosciences, Inc. APTO 372.29 0.00 5.54 -11.91 None
Vermillion, Inc. VRML 368.00 5.00 80.00 -23.53 -307.31
MannKind Corp. MNKD 361.58 62.00 -1.92 -7.78 -74.96
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Progenics Pharmaceuticals, Inc. PGNX 352.60 37.00 11.71 -5.32 -180.28
PDL BioPharma, Inc. PDLI 340.47 54.00 0.61 -3.23 -201.30
Co-Diagnostics, Inc. CODX 340.02 2.00 26.99 -59.03 -334.77
Wave Life Sciences Ltd. WVE 336.94 17.00 17.09 -1.73 None
Rigel Pharmaceuticals, Inc. RIGL 320.88 102.00 4.06 -11.94 -27.39
Seres Therapeutics, Inc. MCRB 319.36 35.00 -5.87 -5.37 -186.09
Cellular Biomedicine Group, Inc. CBMG 316.35 0.00 7.15 -6.12 -776.23
Magenta Therapeutics, Inc. MGTA 310.83 None 2.51 -3.72 None
Brainstorm Cell Therapeutics, Inc. BCLI 292.80 None 39.35 -10.70 None
Immune Design Corp. IMDZ 280.80 2.00 3.08 -5.13 -720.81
Calithera Biosciences, Inc. CALA 278.10 22.00 2.85 -3.08 -245.48
Pfenex, Inc. PFNX 274.56 43.00 3.42 -92.44 -7.03
Cabaletta Bio, Inc. CABA 271.44 None 2.06 -13.00 None
Anavex Life Sciences Corp. AVXL 267.30 None 11.79 -10.31 None
Vaxart, Inc. VXRT 257.95 7.00 17.55 -10.53 -252.86
MediciNova, Inc. MNOV 248.60 6.00 3.40 -22.60 -67.11
Dyadic International, Inc. DYAI 245.97 2.00 7.29 -29.39 -523.67
CymaBay Therapeutics, Inc. CBAY 241.50 10.00 1.38 -2.59 -275.57
CASI Pharmaceuticals, Inc. CASI 235.71 8.00 3.47 -5.06 -614.25
Concert Pharmaceuticals, Inc. CNCE 231.75 0.00 1.78 -3.03 -533.31
IVERIC bio, Inc. ISEE 229.50 210.00 4.32 -3.72 54.39
Eiger BioPharmaceuticals, Inc. EIGR 228.24 None 5.53 -3.40 None
Jounce Therapeutics, Inc. JNCE 227.85 137.00 1.45 5.17 31.23
Lexicon Pharmaceuticals, Inc. LXRX 226.98 321.00 3.80 2.62 26.59
Five Prime Therapeutics, Inc. FPRX 214.20 18.00 1.67 -1.76 -679.63
Strongbridge Biopharma Plc SBBP 202.95 24.00 3.27 -3.69 -181.82
Aduro BioTech, Inc. ADRO 200.00 27.00 3.38 -3.01 -243.93
Chimerix, Inc. CMRX 183.28 11.00 1.94 -1.71 -923.39
Surface Oncology, Inc. SURF 182.70 40.00 2.19 -5.83 -70.90
Alpine Immune Sciences, Inc. ALPN 180.69 3.00 7.10 -5.06 -449.62
XOMA Corp. XOMA 180.27 11.00 5.37 -21.31 -78.07
Paratek Pharmaceuticals, Inc. PRTK 180.25 23.00 -4.02 -1.48 -528.28
ADMA Biologics, Inc. ADMA 176.29 36.00 2.58 -3.32 -151.18
Chiasma, Inc. CHMA 175.89 13.00 2.65 -4.25 -22.14
Viking Therapeutics, Inc. VKTX 167.00 1707.00 0.15 1.11 8.92
Fennec Pharmaceuticals, Inc. FENC 164.40 None 24.91 -11.74 None
Selecta Biosciences, Inc. SELB 164.40 7.00 -27.40 -2.45 -943.39
GlycoMimetics, Inc. GLYC 161.68 9.00 1.10 -3.16 -571.90
Galectin Therapeutics, Inc. GALT 160.60 None 4.11 -11.68 None
Pieris Pharmaceuticals, Inc. PIRS 159.12 51.00 3.22 -7.12 -42.26
Fortress Biotech, Inc. FBIO 156.02 43.00 5.98 -2.83 -124.73
Aravive, Inc. ARAV 151.32 3.00 3.15 -6.22 -796.01
Dermira, Inc. DERM 150.00 11.00 29.30 -13.30 -102.68
Trevena, Inc. TRVN 143.82 0.00 5.67 -5.67 -537.06
X4 Pharmaceuticals, Inc. XFOR 143.52 3.00 1.22 6.06 None
Pluristem Therapeutics, Inc. PSTI 142.72 0.00 15.65 -4.96 -816.51
Minerva Neurosciences, Inc. NERV 138.84 None 7.57 -2.03 None
Verastem, Inc. VSTM 138.61 21.00 2.20 -0.91 -715.40
Harvard Bioscience, Inc. HBIO 137.94 112.00 1.83 -20.17 -6.11
Champions Oncology, Inc. CSBR 137.20 31.00 37.69 -980.00 -0.58
Evofem Biosciences, Inc. EVFM 137.08 0.00 298.00 -1.73 None
Solid Biosciences, Inc. SLDB 132.00 None 2.44 -1.15 None
Applied Genetic Technologies Corp. AGTC 122.17 3.00 1.95 -2.95 -4.81
Eloxx Pharmaceuticals, Inc. ELOX 122.07 0.00 4.82 -2.30 None
Axcella Health, Inc. AXLA 121.67 None 4.04 -1.96 None
Kezar Life Sciences, Inc. KZR 120.75 None 1.96 -3.02 None
La Jolla Pharmaceutical Co. LJPC 119.07 26.00 -1.84 -1.28 -355.86
Lineage Cell Therapeutics, Inc. LCTX 118.50 3.00 1.11 -1.80 -333.12
Aldeyra Therapeutics, Inc. ALDX 116.76 None 2.86 -2.09 None
Palatin Technologies, Inc. PTN 114.24 60.00 1.26 2.67 61.44
Cidara Therapeutics, Inc. CDTX 113.77 23.00 2.80 -2.84 -178.43
Arbutus Biopharma Corp. ABUS 112.80 7.00 -1.94 -0.70 -797.42
Enzo Biochem, Inc. ENZ 111.36 77.00 1.78 -3.57 -39.50
Recro Pharma, Inc. REPH 110.40 96.00 -8.85 -4.30 -25.38
Otonomy, Inc. OTIC 97.96 1.00 3.26 -2.19 None
Savara, Inc. SVRA 95.85 0.00 1.28 -1.13 None
22nd Century Group, Inc. XXII 95.07 27.00 1.75 -3.35 -107.21
Orgenesis, Inc. ORGS 92.64 28.00 1.42 1.92 199.32
Catabasis Pharmaceuticals, Inc. CATB 87.23 1.00 2.24 -3.01 None
BioNTech US, Inc. NTGN 85.96 None 3.01 -1.07 None
DiaMedica Therapeutics, Inc. DMAC 85.80 1.00 7.61 -8.83 None
Windtree Therapeutics, Inc. WINT 84.00 0.00 1.37 -2.93 None
resTORbio, Inc. TORC 83.16 None 1.12 -1.04 None
Monopar Therapeutics, Inc. MNPR 82.28 None 6.39 -20.22 None
Lumos Pharma, Inc. LUMO 81.15 1.00 1.11 -1.67 -429.65
Organovo Holdings, Inc. ONVO 80.60 2.00 3.10 -4.43 -852.00
vTv Therapeutics, Inc. VTVT 79.45 2.00 -2.52 -5.16 -905.13
iBio, Inc. IBIO 78.40 1.00 65.33 -2.02 -884.69
AVEO Pharmaceuticals, Inc. AVEO 78.24 28.00 18.11 97.80 1.62
Catalyst Biosciences, Inc. CBIO 75.53 16.00 1.31 -1.60 -269.75
T2 Biosystems, Inc. TTOO 72.80 9.00 -23.33 -1.19 -646.60
AquaBounty Technologies, Inc. AQB 71.30 0.00 2.84 -5.25 None
ContraFect Corp. CFRX 69.90 None 22.55 -2.00 None
Sesen Bio, Inc. SESN 69.89 0.00 4.15 -0.89 6.31
Proteostasis Therapeutics, Inc. PTI 69.87 5.00 1.36 -1.28 -460.52
Axovant Gene Therapies Ltd. AXGT 68.75 None 1.80 -0.94 None
Anixa Biosciences, Inc. ANIX 66.78 0.00 13.83 -6.91 -14.90
Synlogic, Inc. SYBX 64.35 2.00 0.45 -1.18 None
Sierra Oncology, Inc. SRRA 59.75 None 0.96 -0.45 None
INmune Bio, Inc. INMB 55.00 None 2.42 -6.76 None
Nabriva Therapeutics Plc NBRV 54.92 7.00 4.84 -0.63 None
Idera Pharmaceuticals, Inc. IDRA 54.90 1.00 1.44 -0.78 -236.98
Genocea Biosciences, Inc. GNCA 54.75 0.00 4.87 -1.94 -766.21
Leap Therapeutics, Inc. LPTX 53.82 0.00 6.47 -1.34 None
NeuroBo Pharmaceuticals, Inc. NRBO 51.48 None 18.26 -3.50 None
Infinity Pharmaceuticals, Inc. INFI 50.73 1.00 -22.25 -1.14 -50.81
Equillium, Inc. EQ 47.26 None 1.35 -1.76 None
Actinium Pharmaceuticals, Inc. ATNM 46.79 None 31.40 -2.09 None
Vaccinex, Inc. VCNX 46.62 0.00 -2.16 -1.56 None
Opiant Pharmaceuticals, Inc. OPNT 45.65 39.00 1.15 4.13 29.58
Vascular Biogenics Ltd. VBLT 43.96 1.00 1.85 -2.14 -73.12
Merrimack Pharmaceuticals, Inc. MACK 43.55 144.00 2.48 -6.70 -105.18
Bellicum Pharmaceuticals, Inc. BLCM 41.70 7.00 -5.87 -0.48 -410.63
Outlook Therapeutics, Inc. OTLK 41.28 6.00 -6.79 -1.39 -789.06
Soligenix, Inc. SNGX 41.16 4.00 15.08 -2.76 -346.90
Curis, Inc. CRIS 40.12 11.00 -1.07 -1.24 -292.03
Entasis Therapeutics Holdings, Inc. ETTX 37.96 7.00 2.86 -0.84 -659.64
Miragen Therapeutics, Inc. MGEN 37.10 5.00 2.08 -0.93 -778.69
Zafgen, Inc. ZFGN 36.63 None 0.73 -1.02 None
OncoMed Pharmaceuticals, Inc. OMED 36.48 44.00 0.77 -4.57 -18.24
NanoViricides, Inc. NNVC 36.25 None 4.59 -2.35 None
Armata Pharmaceuticals, Inc. ARMP 35.64 0.00 2.20 -1.77 -167.17
Microbot Medical, Inc. MBOT 35.25 0.00 1.69 -4.61 None
Acorda Therapeutics, Inc. ACOR 35.04 176.00 0.11 -0.15 -131.45
Oragenics, Inc. OGEN 34.50 1.00 7.50 -2.03 -996.00
Pulmatrix, Inc. PULM 34.20 11.00 6.33 -2.38 -188.59
Heat Biologics, Inc. HTBX 33.93 3.00 2.72 -1.61 -633.68
Onconova Therapeutics, Inc. ONTX 30.74 2.00 4.46 -2.52 -876.56
HTG Molecular Diagnostics, Inc. HTGM 30.36 18.00 1.85 -1.62 -106.35
Sunesis Pharmaceuticals, Inc. SNSS 29.00 2.00 3.22 -1.32 -749.95
Alimera Sciences, Inc. ALIM 28.80 56.00 -0.81 -3.13 -15.97
Aptevo Therapeutics, Inc. APVO 27.54 32.00 1.96 -1.72 -78.75
Seelos Therapeutics, Inc. SEEL 27.54 0.00 6.80 0.77 -128.98
NovaBay Pharmaceuticals, Inc. NBY 25.92 7.00 -108.00 -3.72 -112.57
Cleveland BioLabs, Inc. CBLI 24.64 1.00 -6.79 -11.20 -220.48
9 Meters Biopharma, Inc. NMTR 23.68 2.00 -4.92 -0.86 -468.45
Capricor Therapeutics, Inc. CAPR 22.95 1.00 6.85 -2.85 -750.59
Advaxis, Inc. ADXS 22.76 0.00 0.96 -0.28 -79.54
AzurRx BioPharma, Inc. AZRX 22.43 None 8.15 -1.45 None
India Globalization Capital, Inc. IGC 22.40 6.00 0.74 -3.29 -102.76
VistaGen Therapeutics, Inc. VTGN 21.73 1.00 -4.42 -0.91 -929.89
AIM ImmunoTech, Inc. AIM 19.44 0.00 2.31 34.71 None
Conatus Pharmaceuticals, Inc. CNAT 18.48 15.00 1.06 -1.87 -68.87
Correvio Pharma Corp. CORV 18.48 33.00 -41.99 -0.53 -107.81
Iterum Therapeutics Plc ITRM 17.85 0.00 -0.51 -0.18 None
aTyr Pharma, Inc. LIFE 17.04 8.00 0.95 -1.00 -185.14
Bio-Path Holdings, Inc. BPTH 15.21 0.00 1.04 -1.56 None
BioCardia, Inc. BCDA 14.88 1.00 -24.80 -1.02 62.28
Unum Therapeutics, Inc. UMRX 13.35 26.00 0.54 -0.52 -99.09
Diffusion Pharmaceuticals, Inc. DFFN 13.30 0.00 3.17 -0.93 None
Cellectar BioSciences, Inc. CLRB 12.69 0.00 8.29 -0.94 None
Rexahn Pharmaceuticals, Inc. REXN 11.40 1.00 1.21 -1.67 -598.19
SELLAS Life Sciences Group, Inc. SLS 11.12 9.00 2.32 -6.04 -392.81
Aevi Genomic Medicine, Inc. GNMX 10.78 None -4.15 -0.57 None
BioNano Genomics, Inc. BNGO 10.29 9.00 -9.80 -0.32 -345.00
Precipio, Inc. PRPO 9.10 4.00 1.29 -0.49 -499.72
Synthetic Biologics, Inc. SYN 8.50 3.00 -1.72 -0.54 -54.07
ENDRA Life Sciences, Inc. NDRA 8.09 0.00 5.29 -0.40 -538.30
TRACON Pharmaceuticals, Inc. TCON 7.72 3.00 3.78 -0.33 -218.20
ARCA biopharma, Inc. ABIO 6.74 None 2.07 -2.16 None
Ocugen, Inc. OCGN 5.97 0.00 3.16 0.04 None
Achieve Life Sciences, Inc. ACHV 5.60 5.00 1.00 -0.33 -397.65
Cyclacel Pharmaceuticals, Inc. CYCC 4.53 0.00 2.12 -0.53 -748.10
Plus Therapeutics, Inc. PSTV 4.24 6.00 106.00 5.73 -147.01
Xenetic Biosciences, Inc. XBIO 4.16 0.00 0.40 -14.86 -47.40
AIkido Pharma, Inc. AIKI 3.34 0.00 1.39 -0.42 -267.48
Seneca Biopharma, Inc. SNCA 2.92 0.00 1.26 -0.56 None
Tocagen, Inc. TOCA 2.52 0.00 0.96 -0.04 -271.43
Phio Pharmaceuticals Corp. PHIO 2.20 0.00 0.84 -0.15 None
Spherix, Inc. SPEX 1.83 0.00 0.00 -0.37 -267.48
Invivo Therapeutics Holdings Corp. NVIV 1.47 None 0.75 -0.05 None
Sophiris Bio, Inc. SPHS 0.31 5.00 -0.12 -0.04 -222.98
SenesTech, Inc. SNES 0.00 0.00 3.26 -0.01 None

Latest insider transactions

Date Role Name Transaction Quantity Quantity Owned After

Acceleron Pharma (NASDAQ:XLRN) Downgraded to Hold at ValuEngine

28m ago, source: theenterpriseleader.com

Acceleron Pharma (NASDAQ:XLRN) was downgraded by research analysts at ValuEngine from a “buy” rating to a “hold” rating in a ...

Acceleron Announces Pricing of Public Offering of Common Stock

5d ago, source: Associated Press

Acceleron Pharma Inc. (Nasdaq: XLRN), a leading biopharmaceutical company in the discovery, development, and commercialization of TGF-beta superfamily therapeutics to treat serious and rare diseases, ...

Acceleron Pharma stock jumps after positive heart-drug study

11d ago, source: MarketWatch on MSN.com

Acceleron Pharma Inc. undefined shares gained in after-hours trading Wednesday after the pharmaceutical company revealed positive results from a study of ...

Acceleron to Host Conference Call and Webcast to Review Results of PULSAR Phase 2 Trial of Sotatercept Presented at American Thoracic Society 2020 Virtual Conference

13d ago, source: Business Wire

Acceleron Pharma Inc. (Nasdaq: XLRN), a leading biopharmaceutical company in the discovery, development, and ...

Bristol Myers & Acceleron Obtain EC Approval for Reblozyl

6d ago, source: YAHOO!

Bristol Myers Squibb BMY and partner Acceleron Pharma Inc. XLRN announced that the European Commission (EC) has approved ...

Acceleron's Sotatercept Trial, And Other News: The Good, Bad And Ugly Of Biopharma

7d ago, source: Seeking Alpha

Acceleron's sotatercept phase 2 trial yields positive data. Insmed reports positive phase 2 data from the WILLOW study. Chiasma's Mycapssa capsules get FDA appr ...

The Petri Dish: Two new biotech IPOs and a $450M+ licensing deal

3d ago, source: The Business Journals

One local startup out-licensed its promising blood disorder treatments for $450 million, while another plans a $450M stock ...



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