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Stock comparison · Signal date 2026-11-03

IONS vs KNSA: stock comparison and AI forecast

Ionis Pharmaceuticals Inc (IONS) and Kiniksa Pharmaceuticals International, Plc (KNSA) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

Share
Nasdaq · Pharmaceutical Preparations

IONS Ionis Pharmaceuticals Inc

Price
$43.52 -41.8% · 6M
Market Cap
$7.23B
P/E Ratio
–
Size
mid-cap
AI Forecast
NO CURRENT FORECAST
Full analysis →
Nasdaq · Pharmaceutical Preparations

KNSA Kiniksa Pharmaceuticals International, Plc

Market Cap
$7.09B
P/E Ratio
84.1x
Size
mid-cap
AI Forecast
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

IONS · KNSA

Key facts

  • IONS and KNSA have similar market capitalizations ($7.23B and $7.09B).
  • KNSA turns 11.6% of its revenue into net income, against -213.0% for IONS.
  • IONS carries 5.81 times debt per unit of equity, against 0.38 times for KNSA.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricIONSKNSA
Market Cap$7.23B$7.09B
P/E Ratio–84.07x
P/B Ratio16.45x9.99x
EPS$-3.77$1.08
Book Value/Share$2.65$9.09
Revenue/Share$1.60$12.11
FCF/Share$-3.37$2.52

Profitability & Margins

MetricIONSKNSA
ROE-128.5%15.4%
ROA-18.9%11.1%
ROIC-22.2%16.5%
Gross Margin94.0%90.2%
Operating Margin-224.0%13.8%
Net Margin-213.0%11.6%
EBT Margin-211.8%15.4%
Tax Rate-0.6%25.0%

Financial Health

MetricIONSKNSA
Current Ratio7.89x3.91x
Quick Ratio7.73x3.35x
D/E Ratio5.81x0.38x
Financial Leverage6.81x1.38x
Interest Coverage-22.1x–
Working Capital$2.18B$558M

Cash Flow

MetricIONSKNSA
Operating Cash Flow-$496M$199M
Free Cash Flow-$561M$197M
Capital Spending-$64M-$2M
OCF Growth YoY–93.3%
FCF Growth YoY–93.8%
FCF/Sales-211.4%20.9%
CapEx/Sales24.3%0.2%

Operational Efficiency

MetricIONSKNSA
Asset Turnover0.09x0.96x
Receivables Turnover–30.7x
Inventory Turnover0.3x0.9x
Fixed Assets Turnover1.7x383.9x
Days Sales Outstanding–12 days
Days Inventory1158 days424 days
Payables Period1087 days16 days
Cash Conversion Cycle–419 days

Income Statement

MetricIONSKNSA
Total Revenue$265M$946M
Operating Income-$594M$130M
Net Income-$565M$110M
R&D Expense–$136M
SG&A Expense$528M$247M
Cost of Goods Sold$16M$93M

Dividend & Shareholder Information

MetricIONSKNSA
Shares Outstanding166M78M
Net Income Growth–205.1%
FAQ

IONS vs KNSA: stock comparison and AI forecast

Which is bigger, IONS or KNSA?

IONS and KNSA have similar market capitalizations ($7.23B and $7.09B).

Which one does Intratio's AI model rank higher, IONS or KNSA?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

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This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.