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Stock comparison · Signal date 2026-11-03

PTGX vs TGTX: stock comparison and AI forecast

Protagonist Therapeutics, Inc (PTGX) and Tg Therapeutics, Inc. (TGTX) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

Share
Nasdaq · Pharmaceutical Preparations

PTGX Protagonist Therapeutics, Inc

Market Cap
$9.02B
P/E Ratio
176.4x
Size
mid-cap
AI Forecast
Full analysis →
Nasdaq · Pharmaceutical Preparations

TGTX Tg Therapeutics, Inc.

Market Cap
$9.22B
P/E Ratio
21.9x
Size
mid-cap
AI Forecast
NO CURRENT FORECAST
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

PTGX · TGTX

Key facts

  • PTGX and TGTX have similar market capitalizations ($9.02B and $9.22B).
  • TGTX trades at 21.9 times trailing earnings, PTGX at 176.4 times.
  • TGTX carries 1.71 times debt per unit of equity, against 0.05 times for PTGX.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricPTGXTGTX
Market Cap$9.02B$9.22B
P/E Ratio176.41x21.92x
P/B Ratio10.72x15.26x
EPS$0.79$2.65
Book Value/Share$13.01$3.81
Revenue/Share$3.49$5.04
FCF/Share$2.02$0.11

Profitability & Margins

MetricPTGXTGTX
ROE–73.1%
ROA–26.9%
ROIC6.9%9.9%
Gross Margin–82.4%
Operating Margin25.9%17.1%
Net Margin–55.2%
EBT Margin36.4%12.7%
Tax Rate1.7%-334.5%

Financial Health

MetricPTGXTGTX
Current Ratio21.71x4.27x
Quick Ratio–3.72x
D/E Ratio0.05x1.71x
Financial Leverage1.05x2.71x
Interest Coverage–1.2x
Working Capital$770M$877M

Cash Flow

MetricPTGXTGTX
Operating Cash Flow$131M$18M
Free Cash Flow$131M$17M
Capital Spending-$610K-$490K
OCF Growth YoY231.8%–
FCF Growth YoY252.0%–
FCF/Sales57.9%2.2%
CapEx/Sales0.3%0.1%

Operational Efficiency

MetricPTGXTGTX
Asset Turnover0.25x0.49x
Receivables Turnover–2.0x
Inventory Turnover–0.9x
Fixed Assets Turnover65.3x–
Days Sales Outstanding–183 days
Days Inventory–383 days

Income Statement

MetricPTGXTGTX
Total Revenue$226M$800M
Operating Income$58M$136M
Net Income–$441M
R&D Expense$175M$226M
SG&A Expense–$296M
Cost of Goods Sold–$141M

Dividend & Shareholder Information

MetricPTGXTGTX
Shares Outstanding65M159M
Net Income Growth–630.2%
EPS Growth-14.1%846.4%
FAQ

PTGX vs TGTX: stock comparison and AI forecast

Which is bigger, PTGX or TGTX?

PTGX and TGTX have similar market capitalizations ($9.02B and $9.22B).

Which is cheaper on earnings, PTGX or TGTX?

TGTX trades at 21.9 times trailing earnings, PTGX at 176.4 times.

Which one does Intratio's AI model rank higher, PTGX or TGTX?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

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This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.