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Model output · Signal date 2026-10-15

Prelude Therapeutics Inc (PRLD) Stock Forecast Oct. 15, 2026

Analysis updated on Oct. 15, 2026 (UTC) · Alpha · vs marketSwitch to Total · Nasdaq

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Rating · 90D ▲ Bullish Exact rating locked
90-day forecast Sign up free to reveal
30-day forecast Alpha
Rank in coverage Top 35% of 5111 stocks scored
Rank correlation · 90D 3.0% Spearman, 358 dates
Market Cap $343M small-cap · #60 of 60 peers
Summary

Prelude Therapeutics Inc (PRLD) stock forecast summary

Our AI ranks Prelude Therapeutics Inc outside the neutral middle of its coverage (a directional signal). Create a free account and follow it to see the exact price target.

Prelude Therapeutics Inc is a small-cap company with a market capitalization of $343M. It ranks number 60 by market capitalization among the 60 Pharmaceutical Preparations issuers in our coverage with a current forecast.

For PRLD, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 3.0%, measured on 358 forecast dates between 2022-07-28 and 2026-07-17 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 4.0%, measured on 400 forecast dates between 2022-07-28 and 2026-09-15. Across our coverage, the out-of-sample test on 4495 stocks from 2025-01-06 to 2026-07-07 produced a positive net return in 82.5% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

Expected return relative to the market over the horizon: a positive alpha means the model expects the stock to beat the market, whatever the market does. Ratings: strong buy ≥ +1.4%, buy ≥ +0.2%, sell < -0.9%, strong sell < -1.4% (top 15%, next 20%, middle 30%, next 20%, bottom 15% of the 2026-10-15 signals)

A free account shows the exact forecast, rating and rank of 3 tickers you follow, PRLD included.

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Price

PRLD price chart and AI forecast

PRLD
Cross-section · 2026-10-15

How PRLD ranks among 5111 stocks

90D Alpha forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).

Fundamentals · 2026-06-30

Prelude Therapeutics Inc (PRLD) fundamentals

Trailing twelve months. The industry median and the rank (1 = highest) are taken over the Pharmaceutical Preparations peers listed below that report each metric.

Valuation & Market

MetricPRLDIndustry medianRank
Market Cap $343M $12.69B 60/60
P/B Ratio 2.56x 7.20x 37/41
EPS $-1.02 – –
Book Value/Share $1.26 – –
Revenue/Share $0.21 – –
FCF/Share $-0.31 – –

Profitability & Margins

MetricPRLDIndustry medianRank
ROE -45.2% 6.3% 27/36
ROA -31.9% -1.2% 34/41
ROIC -44.5% -0.4% 35/44
Operating Margin -300.6% 12.4% 34/37
Net Margin -269.8% 6.8% 30/33
EBT Margin -278.0% 10.6% 41/44

Financial Health

MetricPRLDIndustry medianRank
Current Ratio 4.07x 3.06x 18/56
D/E Ratio 0.42x 1.23x 31/46
Financial Leverage 1.42x 2.09x 30/46
Working Capital $117M $945M 50/56

Cash Flow

MetricPRLDIndustry medianRank
Operating Cash Flow -$33M $183M 37/56
Free Cash Flow -$33M $164M 30/47
Capital Spending $0.00M -$46M 1/47
FCF/Sales -148.3% 16.8% 37/40
CapEx/Sales 0.0% 2.5% 40/40

Operational Efficiency

MetricPRLDIndustry medianRank
Asset Turnover 0.12x 0.48x 36/39
Fixed Assets Turnover 5.1x 7.6x 25/41

Income Statement

MetricPRLDIndustry medianRank
Total Revenue $22M $2.83B 43/44
Operating Income -$67M $32M 28/48
Net Income -$60M -$38M 25/43
R&D Expense $69M $548M 53/55

Dividend & Shareholder Information

MetricPRLDIndustry medianRank
Shares Outstanding 106M – –

Balance Sheet Highlights (USD millions)

Total Current Assets$155M81.7% of assets
Cash & Short-term Investments$26M13.9% of assets
Total Liabilities$56M29.3% of assets
Short-term Debt$36M19.0% of assets
Quarterly Financial Reports

PRLD quarterly financials and insider trading

Industry Peers · Pharmaceutical Preparations

Prelude Therapeutics Inc (PRLD) industry peers

Companies classified under the same SEC industry code as Prelude Therapeutics Inc (Pharmaceutical Preparations): 60 common-stock issuers with a forecast this week, one row per issuer, largest first. This is a classification match, not a curated list of competitors.

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Company 90-Day AI Forecast (Alpha) Market Cap P/E Ratio P/B Ratio
PRLD Prelude Therapeutics Inc ▲ $343M – 2.6x
LLY Eli Lilly & Co ▶ $1.14T 40.6x 115.8x
JNJ Johnson & Johnson ▼ $611.90B 29.5x 7.2x
ABBV Abbvie Inc. ▶ $500.75B 73.2x –
MRK Merck & Co., Inc. ▶ $363.59B 117.9x 8.7x
NVS Novartis Ag ▼ $280.27B 8.8x –
AZN Astrazeneca Plc ▼ $258.35B 12.0x –
ABT Abbott Laboratories ▼ $182.04B 29.3x 3.5x
NVO Novo Nordisk A S ▼ $169.41B 2.8x –
PFE Pfizer Inc ▼ $166.49B 36.1x 2.0x
VRTX Vertex Pharmaceuticals Inc / Ma ▼ $126.35B 28.7x 6.2x
BMY Bristol Myers Squibb Co ▶ $123.73B 13.3x 5.5x
SNY Sanofi ▼ $98.05B – –
GSK Gsk Plc ▼ $96.58B 5.3x –
REGN Regeneron Pharmaceuticals, Inc. ▶ $80.48B 19.3x 2.5x
TEVA Teva Pharmaceutical Industries Ltd ▶ $47.45B 67.1x 6.1x
ONC Beone Medicines Ltd. ▲ $39.96B 1212.0x 7.7x
RPRX Royalty Pharma Plc ▲ $33.92B 41.6x 5.0x
ALNY Alnylam Pharmaceuticals, Inc. ▶ $31.32B 58.8x 23.1x
ZTS Zoetis Inc. ▼ $31.11B 11.9x 9.9x
TAK Takeda Pharmaceutical Co Ltd ▶ $30.24B – –
ATHE Alterity Therapeutics Ltd ▶ $25.65B – –
ZLAB Zai Lab Ltd ▶ $25.26B – 41.6x
ROIV Roivant Sciences Ltd. ▲ $24.28B – 5.7x
GMAB Genmab A/S ▶ $23.73B 1.5x –
UTHR United Therapeutics Corp ▼ $23.16B 17.7x 3.6x
INSM Insmed Inc ▶ $21.36B – 28.2x
VTRS Viatris Inc ▶ $20.03B – –
ASND Ascendis Pharma A/S ▲ $14.94B – –
JAZZ Jazz Pharmaceuticals Plc ▼ $13.61B 14.3x 2.8x
BBIO Bridgebio Pharma, Inc. ▶ $13.12B – –
CORT Corcept Therapeutics Inc ▲ $12.26B 127.4x 17.4x
SMMT Summit Therapeutics Inc. ▶ $12.07B – 19.2x
ELAN Elanco Animal Health Inc ▼ $11.76B – 1.8x
BMRN Biomarin Pharmaceutical Inc ▶ $10.85B 70.1x 1.7x
RDY Dr Reddys Laboratories Ltd ▼ $10.64B 14.0x –
MDGL Madrigal Pharmaceuticals, Inc. ▶ $10.63B – 20.3x
CYTK Cytokinetics Inc ▲ $8.89B – –
PTGX Protagonist Therapeutics, Inc ▶ $8.82B 172.5x 10.5x
AXSM Axsome Therapeutics, Inc. ▲ $8.47B – 101.7x
ARWR Arrowhead Pharmaceuticals, Inc. ▲ $8.26B – 17.8x
ABVX Abivax S.A. ▼ $7.26B – –
IONS Ionis Pharmaceuticals Inc ▲ $7.10B – 16.1x
SYRE Spyre Therapeutics, Inc. ▲ $6.93B – 6.3x
ALKS Alkermes Plc. ▲ $6.73B 44.1x 3.7x
PRAX Praxis Precision Medicines, Inc. ▲ $6.67B – 5.0x
KNSA Kiniksa Pharmaceuticals International, Plc ▼ $6.16B 86.6x 10.2x
AMRX Amneal Pharmaceuticals, Inc. ▲ $6.15B 58.3x –
BLTE Belite Bio, Inc ▲ $6.00B – 7.8x
RYTM Rhythm Pharmaceuticals, Inc. ▶ $5.97B – 58.0x
LGND Ligand Pharmaceuticals Inc ▶ $5.88B 28.6x 6.1x
BLRX Biolinerx Ltd. ▶ $5.43B – –
MIRM Mirum Pharmaceuticals, Inc. ▲ $5.19B – –
ERAS Erasca, Inc. ▲ $5.14B – 14.2x
COGT Cogent Biosciences, Inc. ▶ $5.12B – 9.6x
ORKA Oruka Therapeutics, Inc. ▲ $5.08B – 4.6x
TVTX Travere Therapeutics, Inc. ▲ $5.02B – 204.8x
PTCT Ptc Therapeutics, Inc. ▲ $4.98B – –
MANE Veradermics, Inc ▲ $4.74B – 5.8x
DNTH Dianthus Therapeutics, Inc. /De/ ▲ $4.17B – 3.6x

Where PRLD sits on the market map

Life Sciences · Pharmaceutical Preparations
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News

Prelude Therapeutics Inc (PRLD) stock news

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FAQ

Prelude Therapeutics Inc (PRLD) stock forecast FAQ

What is the Prelude Therapeutics Inc (PRLD) stock forecast?

Our AI ranks Prelude Therapeutics Inc outside the neutral middle of its coverage (a directional signal). Create a free account and follow it to see the exact price target.

How accurate are Prelude Therapeutics Inc stock predictions?

For PRLD, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 3.0%, measured on 358 forecast dates between 2022-07-28 and 2026-07-17 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 4.0%, measured on 400 forecast dates between 2022-07-28 and 2026-09-15. Across our coverage, the out-of-sample test on 4495 stocks from 2025-01-06 to 2026-07-07 produced a positive net return in 82.5% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

How often are Prelude Therapeutics Inc forecasts updated?

Prelude Therapeutics Inc forecasts are refreshed on trading days as the daily model run completes. The forecast on this page was produced on Oct. 15, 2026.

Which companies are Prelude Therapeutics Inc's industry peers?

60 issuers in our coverage, PRLD included, share the SEC industry code Pharmaceutical Preparations. The largest are: Eli Lilly & Co (LLY), Johnson & Johnson (JNJ), Abbvie Inc. (ABBV), Merck & Co., Inc. (MRK), Novartis Ag (NVS), Astrazeneca Plc (AZN).

This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.