Oruka Therapeutics, Inc. (ORKA) Stock Forecast Oct. 15, 2026
Analysis updated on Oct. 15, 2026 (UTC) · Alpha · vs marketSwitch to Total · Nasdaq
Oruka Therapeutics, Inc. (ORKA) stock forecast summary
Our AI ranks Oruka Therapeutics, Inc. outside the neutral middle of its coverage (a directional signal). Create a free account and follow it to see the exact price target.
Oruka Therapeutics, Inc. is a mid-cap company with a market capitalization of $5.08B. It ranks number 54 by market capitalization among the 60 Pharmaceutical Preparations issuers in our coverage with a current forecast.
For ORKA, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 49.0%, measured on 358 forecast dates between 2022-07-28 and 2026-07-17 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 32.0%, measured on 400 forecast dates between 2022-07-28 and 2026-09-15. Across our coverage, the out-of-sample test on 4495 stocks from 2025-01-06 to 2026-07-07 produced a positive net return in 82.5% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report
Expected return relative to the market over the horizon: a positive alpha means the model expects the stock to beat the market, whatever the market does. Ratings: strong buy ≥ +1.3%, buy ≥ +0.4%, sell < -0.8%, strong sell < -1.5% (top 15%, next 20%, middle 30%, next 20%, bottom 15% of the 2026-10-15 signals)
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How ORKA ranks among 5111 stocks
90D Alpha forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).
Oruka Therapeutics, Inc. (ORKA) fundamentals
Trailing twelve months. The industry median and the rank (1 = highest) are taken over the Pharmaceutical Preparations peers listed below that report each metric.
Valuation & Market
| Metric | ORKA | Rank |
|---|---|---|
| Market Cap | $5.08B | 54/60 |
| P/B Ratio | 4.56x | 31/40 |
| EPS | $-4.15 | – |
| Book Value/Share | $16.83 | – |
| FCF/Share | $-1.53 | – |
Profitability & Margins
| Metric | ORKA | Rank |
|---|---|---|
| ROIC | -13.9% | 28/43 |
Financial Health
| Metric | ORKA | Rank |
|---|---|---|
| Current Ratio | 38.51x | 3/55 |
| D/E Ratio | 0.02x | 43/45 |
| Financial Leverage | 1.02x | 42/44 |
| Interest Coverage | -15.9x | 25/35 |
| Working Capital | $862M | 29/55 |
Cash Flow
| Metric | ORKA | Rank |
|---|---|---|
| Operating Cash Flow | -$101M | 39/54 |
| Free Cash Flow | -$101M | 33/46 |
| Capital Spending | -$230K | 2/46 |
Income Statement
| Metric | ORKA | Rank |
|---|---|---|
| Operating Income | -$155M | 28/46 |
| R&D Expense | $129M | 48/53 |
Dividend & Shareholder Information
| Metric | ORKA | Rank |
|---|---|---|
| Shares Outstanding | 66M | – |
Balance Sheet Highlights (USD millions)
| Total Current Assets | $885M | 77.7% of assets |
| Cash & Short-term Investments | $268M | 23.6% of assets |
| Total Liabilities | $25M | 2.2% of assets |
ORKA quarterly financials and insider trading
Oruka Therapeutics, Inc. (ORKA) industry peers
Companies classified under the same SEC industry code as Oruka Therapeutics, Inc. (Pharmaceutical Preparations): 60 common-stock issuers with a forecast this week, one row per issuer, largest first. This is a classification match, not a curated list of competitors.
Reveal all forecasts · See exact % predictions for all competitors
Sign up free| Company | 90-Day AI Forecast (Alpha) | Market Cap |
|---|---|---|
| ORKA Oruka Therapeutics, Inc. | ▲ | $5.08B |
| LLY Eli Lilly & Co | ▶ | $1.14T |
| JNJ Johnson & Johnson | ▼ | $611.90B |
| ABBV Abbvie Inc. | ▶ | $500.94B |
| MRK Merck & Co., Inc. | ▶ | $363.59B |
| NVS Novartis Ag | ▼ | $280.27B |
| AZN Astrazeneca Plc | ▼ | $251.15B |
| ABT Abbott Laboratories | ▼ | $179.05B |
| NVO Novo Nordisk A S | ▼ | $169.41B |
| PFE Pfizer Inc | ▼ | $166.49B |
| VRTX Vertex Pharmaceuticals Inc / Ma | ▼ | $126.35B |
| BMY Bristol Myers Squibb Co | ▶ | $121.09B |
| GSK Gsk Plc | ▼ | $96.58B |
| REGN Regeneron Pharmaceuticals, Inc. | ▶ | $80.14B |
| SNY Sanofi | ▼ | $48.50B |
| TEVA Teva Pharmaceutical Industries Ltd | ▶ | $47.45B |
| ONC Beone Medicines Ltd. | ▲ | $39.96B |
| RPRX Royalty Pharma Plc | ▲ | $33.92B |
| ZTS Zoetis Inc. | ▼ | $31.11B |
| TAK Takeda Pharmaceutical Co Ltd | ▼ | $30.24B |
| ALNY Alnylam Pharmaceuticals, Inc. | ▶ | $30.04B |
| ATHE Alterity Therapeutics Ltd | ▶ | $25.65B |
| ZLAB Zai Lab Ltd | ▶ | $25.26B |
| ROIV Roivant Sciences Ltd. | ▶ | $24.28B |
| GMAB Genmab A/S | ▶ | $23.73B |
| UTHR United Therapeutics Corp | ▼ | $23.16B |
| INSM Insmed Inc | ▶ | $21.36B |
| VTRS Viatris Inc | ▶ | $20.03B |
| ASND Ascendis Pharma A/S | ▲ | $14.97B |
| JAZZ Jazz Pharmaceuticals Plc | ▼ | $13.61B |
| BBIO Bridgebio Pharma, Inc. | ▶ | $12.69B |
| CORT Corcept Therapeutics Inc | ▲ | $12.56B |
| SMMT Summit Therapeutics Inc. | ▶ | $12.07B |
| ELAN Elanco Animal Health Inc | ▼ | $11.27B |
| BMRN Biomarin Pharmaceutical Inc | ▶ | $10.67B |
| RDY Dr Reddys Laboratories Ltd | ▼ | $10.64B |
| MDGL Madrigal Pharmaceuticals, Inc. | ▶ | $10.63B |
| PTGX Protagonist Therapeutics, Inc | ▶ | $8.82B |
| CYTK Cytokinetics Inc | ▲ | $8.82B |
| AXSM Axsome Therapeutics, Inc. | ▲ | $8.50B |
| ARWR Arrowhead Pharmaceuticals, Inc. | ▲ | $8.25B |
| ABVX Abivax S.A. | ▼ | $7.68B |
| IONS Ionis Pharmaceuticals Inc | ▲ | $7.10B |
| SYRE Spyre Therapeutics, Inc. | ▲ | $6.93B |
| PRAX Praxis Precision Medicines, Inc. | ▶ | $6.67B |
| ALKS Alkermes Plc. | ▲ | $6.56B |
| KNSA Kiniksa Pharmaceuticals International, Plc | ▼ | $6.16B |
| AMRX Amneal Pharmaceuticals, Inc. | ▶ | $6.04B |
| BLTE Belite Bio, Inc | ▲ | $6.01B |
| RYTM Rhythm Pharmaceuticals, Inc. | ▶ | $5.97B |
| LGND Ligand Pharmaceuticals Inc | ▼ | $5.88B |
| BLRX Biolinerx Ltd. | ▶ | $5.43B |
| MIRM Mirum Pharmaceuticals, Inc. | ▲ | $5.19B |
| ERAS Erasca, Inc. | ▲ | $5.14B |
| TVTX Travere Therapeutics, Inc. | ▲ | $5.02B |
| PTCT Ptc Therapeutics, Inc. | ▶ | $4.98B |
| COGT Cogent Biosciences, Inc. | ▶ | $4.88B |
| MANE Veradermics, Inc | ▲ | $4.74B |
| DNTH Dianthus Therapeutics, Inc. /De/ | ▲ | $4.18B |
| INDV Indivior Pharmaceuticals, Inc. | ▼ | $4.03B |
Where ORKA sits on the market map
Oruka Therapeutics, Inc. (ORKA) stock news
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Oruka Therapeutics, Inc. (ORKA) stock forecast FAQ
What is the Oruka Therapeutics, Inc. (ORKA) stock forecast?
Our AI ranks Oruka Therapeutics, Inc. outside the neutral middle of its coverage (a directional signal). Create a free account and follow it to see the exact price target.
How accurate are Oruka Therapeutics, Inc. stock predictions?
For ORKA, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 49.0%, measured on 358 forecast dates between 2022-07-28 and 2026-07-17 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 32.0%, measured on 400 forecast dates between 2022-07-28 and 2026-09-15. Across our coverage, the out-of-sample test on 4495 stocks from 2025-01-06 to 2026-07-07 produced a positive net return in 82.5% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report
How often are Oruka Therapeutics, Inc. forecasts updated?
Oruka Therapeutics, Inc. forecasts are refreshed on trading days as the daily model run completes. The forecast on this page was produced on Oct. 15, 2026.
Which companies are Oruka Therapeutics, Inc.'s industry peers?
60 issuers in our coverage, ORKA included, share the SEC industry code Pharmaceutical Preparations. The largest are: Eli Lilly & Co (LLY), Johnson & Johnson (JNJ), Abbvie Inc. (ABBV), Merck & Co., Inc. (MRK), Novartis Ag (NVS), Astrazeneca Plc (AZN).
This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.