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Stock comparison · Signal date 2026-11-09

PRAX vs PTGX: stock comparison and AI forecast

Praxis Precision Medicines, Inc. (PRAX) and Protagonist Therapeutics, Inc (PTGX) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

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Nasdaq · Pharmaceutical Preparations

PRAX Praxis Precision Medicines, Inc.

Market Cap
$7.75B
P/E Ratio
–
Size
mid-cap
AI Forecast
Full analysis →
Nasdaq · Pharmaceutical Preparations

PTGX Protagonist Therapeutics, Inc

Market Cap
$8.54B
P/E Ratio
33.6x
Size
mid-cap
AI Forecast
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

PRAX · PTGX

Key facts

  • PTGX is 1.1 times larger than PRAX by market capitalization ($8.54B against $7.75B).
  • PTGX carries 0.06 times debt per unit of equity, against 0.04 times for PRAX.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricPRAXPTGX
Market Cap$7.75B$8.54B
P/E Ratio–33.60x
P/B Ratio5.78x7.88x
EPS$-12.95$3.93
Book Value/Share$48.03$16.77
Revenue/Share–$3.39
FCF/Share$-10.94$1.69

Profitability & Margins

MetricPRAXPTGX
ROE-25.3%31.6%
ROA-24.4%29.9%
ROIC-28.2%29.6%
Operating Margin–147.1%
Net Margin–155.8%
EBT Margin–158.4%
Tax Rate–2.3%

Financial Health

MetricPRAXPTGX
Current Ratio15.73x19.85x
D/E Ratio0.04x0.06x
Financial Leverage1.04x1.06x
Working Capital$723M$1.05B

Cash Flow

MetricPRAXPTGX
Operating Cash Flow-$305M$110M
Free Cash Flow-$305M$109M
Capital Spending-$310K-$760K
OCF Growth YoY–67.9%
FCF Growth YoY–71.3%
FCF/Sales–49.7%
CapEx/Sales–0.3%

Operational Efficiency

MetricPRAXPTGX
Asset Turnover–0.19x
Fixed Assets Turnover–66.1x

Income Statement

MetricPRAXPTGX
Total Revenue–$220M
Operating Income-$378M$323M
Net Income-$339M$342M
R&D Expense$291M$176M

Dividend & Shareholder Information

MetricPRAXPTGX
Shares Outstanding28M65M
Net Income Growth–645.5%
EPS Growth–182.7%
FAQ

PRAX vs PTGX: stock comparison and AI forecast

Which is bigger, PRAX or PTGX?

PTGX is 1.1 times larger than PRAX by market capitalization ($8.54B against $7.75B).

Which one does Intratio's AI model rank higher, PRAX or PTGX?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

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This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.