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Model output · Signal date 2026-11-12

Alnylam Pharmaceuticals, Inc. (ALNY) Stock Forecast Nov. 12, 2026

Analysis updated on Nov. 12, 2026 (UTC) · Alpha · vs marketSwitch to Total · Nasdaq

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Rating · 90D Unlock rating and forecasts
90-day forecast Sign up free to reveal
30-day forecast Alpha
Rank in coverage of 4226 stocks scored
Rank correlation · 90D 50.0% Spearman, 358 dates
Market Cap $21.41B large-cap · #25 of 60 peers
Summary

Alnylam Pharmaceuticals, Inc. (ALNY) stock forecast summary

Our AI scores Alnylam Pharmaceuticals, Inc. every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.

Alnylam Pharmaceuticals, Inc. is a large-cap company with a market capitalization of $21.41B. It ranks number 25 by market capitalization among the 60 Pharmaceutical Preparations issuers in our coverage with a current forecast.

For ALNY, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 50.0%, measured on 358 forecast dates between 2022-08-25 and 2026-08-14 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 37.0%, measured on 400 forecast dates between 2022-08-25 and 2026-10-13. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

Expected return relative to the market over the horizon: a positive alpha means the model expects the stock to beat the market, whatever the market does. Ratings: strong buy ≥ +3.2%, buy ≥ +1.6%, sell < -0.4%, strong sell < -1.7% (top 15%, next 20%, middle 30%, next 20%, bottom 15% of the 2026-11-11 signals)

A free account shows the exact forecast, rating and rank of 3 tickers you follow, ALNY included.

Price

ALNY price chart and AI forecast

ALNY
Cross-section · 2026-11-11

How ALNY ranks among 4226 stocks

90D Alpha forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).

Fundamentals · 2026-09-30

Alnylam Pharmaceuticals, Inc. (ALNY) fundamentals

Trailing twelve months. The industry median and the rank (1 = highest) are taken over the Pharmaceutical Preparations peers listed below that report each metric.

Valuation & Market

MetricALNYIndustry medianRank
Market Cap $21.41B $12.82B 25/60
P/E Ratio 7.52x 37.89x 27/32
P/B Ratio 5.94x 7.88x 29/42
EPS $21.27 – –
Book Value/Share $26.91 – –

Profitability & Margins

MetricALNYIndustry medianRank
ROE 76.8% 5.3% 2/39
ROA 34.6% 1.9% 3/43
ROIC 22.7% -1.6% 6/46
Gross Margin 78.7% 82.7% 20/35
Operating Margin 21.5% 9.2% 11/39
Net Margin 44.2% 6.3% 2/35
EBT Margin 17.5% 10.3% 17/46
Tax Rate -174.3% – –

The effective tax rate is outside the normal band, which points to a large non-recurring tax item in the trailing twelve months; headline net income, net margin and P/E are affected by it.

Financial Health

MetricALNYIndustry medianRank
Current Ratio 2.48x 2.46x 29/58
Quick Ratio 2.43x 1.44x 14/43
D/E Ratio 1.22x 1.22x 24/47
Financial Leverage 2.22x 2.12x 22/47
Interest Coverage 4.7x 1.1x 12/34
Working Capital $3.05B $920M 14/58

Cash Flow

MetricALNYIndustry medianRank
Operating Cash Flow $1.23B $198M 24/60

Operational Efficiency

MetricALNYIndustry medianRank
Inventory Turnover 12.6x 1.6x 2/34
Days Inventory 29 days 234 days 33/34
Payables Period 37 days 124 days 22/24

Income Statement

MetricALNYIndustry medianRank
Operating Income $1.35B $44M 14/52
Net Income $2.77B $51M 13/47
R&D Expense $1.92B $536M 17/59
SG&A Expense $1.66B $1.43B 18/41
Cost of Goods Sold $1.33B $1.89B 21/36

Dividend & Shareholder Information

MetricALNYIndustry medianRank
Shares Outstanding 134M – –

Balance Sheet Highlights (USD millions)

Total Current Assets$5.11B63.9% of assets
Cash & Short-term Investments$1.75B21.9% of assets
Accounts Receivable$1.08B13.6% of assets
Inventory$106M1.3% of assets
Total Liabilities$4.39B54.9% of assets
Short-term Debt$1.93B24.1% of assets
Quarterly Financial Reports

ALNY quarterly financials and insider trading

Industry Peers · Pharmaceutical Preparations

Alnylam Pharmaceuticals, Inc. (ALNY) industry peers

Companies classified under the same SEC industry code as Alnylam Pharmaceuticals, Inc. (Pharmaceutical Preparations): 60 common-stock issuers with a forecast this week, one row per issuer, largest first. This is a classification match, not a curated list of competitors.

Reveal all forecasts · See exact % predictions for all competitors

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Company 90-Day AI Forecast (Alpha) Market Cap P/E Ratio P/B Ratio
ALNY Alnylam Pharmaceuticals, Inc. $21.41B 7.5x 5.9x
LLY Eli Lilly & Co $1.35T 46.5x 137.1x
JNJ Johnson & Johnson $675.92B 42.7x 8.3x
ABBV Abbvie Inc. $521.26B 45.2x –
MRK Merck & Co., Inc. $365.26B 152.6x 8.1x
NVS Novartis Ag $311.52B 9.8x –
AZN Astrazeneca Plc $287.49B 13.4x –
ABT Abbott Laboratories $190.04B 38.6x 3.7x
NVO Novo Nordisk A S $180.87B 3.0x –
PFE Pfizer Inc $167.34B 37.2x 1.9x
VRTX Vertex Pharmaceuticals Inc / Ma $138.87B 35.3x 6.6x
BMY Bristol Myers Squibb Co $128.59B 13.9x 5.5x
SNY Sanofi $118.90B – –
GSK Gsk Plc $102.08B 5.6x –
REGN Regeneron Pharmaceuticals, Inc. $94.31B 20.3x 2.8x
TAK Takeda Pharmaceutical Co Ltd $65.38B 6.3x –
TEVA Teva Pharmaceutical Industries Ltd $49.41B 40.8x 6.2x
ONC Beone Medicines Ltd. $48.20B 1177.8x 8.3x
GMAB Genmab A/S $34.66B 2.2x –
ZTS Zoetis Inc. $34.07B 14.0x 10.3x
ROIV Roivant Sciences Ltd. $29.75B – 7.4x
RPRX Royalty Pharma Plc $29.74B 48.6x 4.4x
INSM Insmed Inc $26.21B – 36.1x
UTHR United Therapeutics Corp $25.25B 22.3x 4.0x
VTRS Viatris Inc $23.95B – –
ASND Ascendis Pharma A/S $17.03B – –
JAZZ Jazz Pharmaceuticals Plc $15.93B 81.0x 3.8x
BBIO Bridgebio Pharma, Inc. $15.49B – –
SMMT Summit Therapeutics Inc. $14.22B – 25.2x
ELAN Elanco Animal Health Inc $13.23B – 2.0x
RDY Dr Reddys Laboratories Ltd $12.40B 16.3x –
BMRN Biomarin Pharmaceutical Inc $11.29B 583.3x 1.8x
TGTX Tg Therapeutics, Inc. $10.20B 93.1x 17.8x
MDGL Madrigal Pharmaceuticals, Inc. $9.99B – 15.9x
PRAX Praxis Precision Medicines, Inc. $9.43B – 7.5x
SYRE Spyre Therapeutics, Inc. $9.21B – 8.8x
PTGX Protagonist Therapeutics, Inc $8.82B 34.7x 8.1x
CYTK Cytokinetics Inc $8.14B – –
CORT Corcept Therapeutics Inc $8.06B 44.6x 9.7x
ALKS Alkermes Plc. $8.03B 46.5x 4.3x
RYTM Rhythm Pharmaceuticals, Inc. $7.85B – 89.2x
AXSM Axsome Therapeutics, Inc. $7.82B – 74.1x
KNSA Kiniksa Pharmaceuticals International, Plc $7.47B 88.0x 10.5x
ORKA Oruka Therapeutics, Inc. $7.25B – 6.1x
ABVX Abivax S.A. $7.18B – –
ARWR Arrowhead Pharmaceuticals, Inc. $6.97B – 15.0x
AMRX Amneal Pharmaceuticals, Inc. $6.93B 144.7x –
LGND Ligand Pharmaceuticals Inc $6.28B 119.9x 6.5x
MANE Veradermics, Inc $6.20B – 7.8x
BLTE Belite Bio, Inc $6.13B – 8.0x
MIRM Mirum Pharmaceuticals, Inc. $6.13B – –
ERAS Erasca, Inc. $5.88B – 16.2x
SUPN Supernus Pharmaceuticals, Inc. $5.56B – 5.2x
PTCT Ptc Therapeutics, Inc. $5.36B – –
EWTX Edgewise Therapeutics, Inc. $5.17B 5.7x 3.2x
COGT Cogent Biosciences, Inc. $5.10B – 9.9x
DNTH Dianthus Therapeutics, Inc. /De/ $4.99B – 4.0x
IONS Ionis Pharmaceuticals Inc $4.71B – 12.0x
TVTX Travere Therapeutics, Inc. $4.65B – 206.1x
LQDA Liquidia Corp $4.60B – –

Where ALNY sits on the market map

Life Sciences · Pharmaceutical Preparations
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News

Alnylam Pharmaceuticals, Inc. (ALNY) stock news

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FAQ

Alnylam Pharmaceuticals, Inc. (ALNY) stock forecast FAQ

What is the Alnylam Pharmaceuticals, Inc. (ALNY) stock forecast?

Our AI scores Alnylam Pharmaceuticals, Inc. every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.

How accurate are Alnylam Pharmaceuticals, Inc. stock predictions?

For ALNY, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 50.0%, measured on 358 forecast dates between 2022-08-25 and 2026-08-14 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 37.0%, measured on 400 forecast dates between 2022-08-25 and 2026-10-13. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

How often are Alnylam Pharmaceuticals, Inc. forecasts updated?

Alnylam Pharmaceuticals, Inc. forecasts are refreshed on trading days as the daily model run completes. The forecast on this page was produced on Nov. 12, 2026.

Which companies are Alnylam Pharmaceuticals, Inc.'s industry peers?

60 issuers in our coverage, ALNY included, share the SEC industry code Pharmaceutical Preparations. The largest are: Eli Lilly & Co (LLY), Johnson & Johnson (JNJ), Abbvie Inc. (ABBV), Merck & Co., Inc. (MRK), Novartis Ag (NVS), Astrazeneca Plc (AZN).

This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.