Denali Therapeutics Inc. (DNLI) Stock Forecast Nov. 6, 2026
Analysis updated on Nov. 6, 2026 (UTC) · Total · absolute moveSwitch to Alpha · Nasdaq
Denali Therapeutics Inc. (DNLI) stock forecast summary
Our AI scores Denali Therapeutics Inc. every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.
Denali Therapeutics Inc. is a mid-cap company with a market capitalization of $3.21B. It ranks number 28 by market capitalization among the 60 Biological Products, (No Diagnostic Substances) issuers in our coverage with a current forecast.
For DNLI, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 1.0%, measured on 357 forecast dates between 2022-08-19 and 2026-08-07 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 10.0%, measured on 400 forecast dates between 2022-08-19 and 2026-10-07. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report
Expected absolute price move over the horizon, market included. This is the number a price target is built from. Ratings: strong buy ≥ +6.2%, buy ≥ +4.2%, sell < +2.1%, strong sell < +0.4% (top 15%, next 20%, middle 30%, next 20%, bottom 15% of the 2026-11-06 signals)
A free account shows the exact forecast, rating and rank of 3 tickers you follow, DNLI included.
DNLI price chart and AI forecast
How DNLI ranks among 5150 stocks
90D Total forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).
Denali Therapeutics Inc. (DNLI) fundamentals
Trailing twelve months. The industry median and the rank (1 = highest) are taken over the Biological Products, (No Diagnostic Substances) peers listed below that report each metric.
Valuation & Market
| Metric | DNLI | Rank |
|---|---|---|
| Market Cap | $3.21B | 28/60 |
| P/B Ratio | 3.46x | 34/48 |
| EPS | $-1.82 | – |
| Book Value/Share | $5.80 | – |
| FCF/Share | $-2.82 | – |
Profitability & Margins
| Metric | DNLI | Rank |
|---|---|---|
| ROE | -33.9% | 23/43 |
| ROA | -25.0% | 26/46 |
| ROIC | -45.8% | 41/52 |
| Operating Margin | -2992.5% | 36/40 |
| Net Margin | -1768.6% | 30/35 |
| EBT Margin | -2992.5% | 38/42 |
Financial Health
| Metric | DNLI | Rank |
|---|---|---|
| Current Ratio | 6.21x | 28/59 |
| Quick Ratio | 5.94x | 7/29 |
| D/E Ratio | 0.36x | 28/51 |
| Financial Leverage | 1.36x | 27/50 |
| Working Capital | $496M | 24/58 |
Cash Flow
| Metric | DNLI | Rank |
|---|---|---|
| Operating Cash Flow | -$444M | 52/56 |
| Free Cash Flow | -$450M | 44/49 |
| Capital Spending | -$6M | 25/49 |
Income Statement
| Metric | DNLI | Rank |
|---|---|---|
| Operating Income | -$532M | 47/53 |
| Net Income | -$314M | 35/46 |
| R&D Expense | $405M | 17/55 |
Dividend & Shareholder Information
| Metric | DNLI | Rank |
|---|---|---|
| Shares Outstanding | 160M | – |
Balance Sheet Highlights (USD millions)
| Total Current Assets | $592M | 47.1% of assets |
| Cash & Short-term Investments | $103M | 8.2% of assets |
| Accounts Receivable | $19M | 1.5% of assets |
| Inventory | $26M | 2.1% of assets |
| Total Liabilities | $330M | 26.2% of assets |
| Short-term Debt | $82M | 6.5% of assets |
DNLI quarterly financials and insider trading
Denali Therapeutics Inc. (DNLI) industry peers
Companies classified under the same SEC industry code as Denali Therapeutics Inc. (Biological Products, (No Diagnostic Substances)): 60 common-stock issuers with a forecast this week, one row per issuer, largest first. This is a classification match, not a curated list of competitors.
Reveal all forecasts · See exact % predictions for all competitors
Sign up free| Company | 90-Day AI Forecast (Total) | Market Cap |
|---|---|---|
| DNLI Denali Therapeutics Inc. | $3.21B | |
| AMGN Amgen Inc | $248.92B | |
| GILD Gilead Sciences, Inc. | $207.00B | |
| MRNA Moderna, Inc. | $101.48B | |
| ARGX Argenx Se | $57.38B | |
| RVMD Revolution Medicines, Inc. | $38.08B | |
| BIIB Biogen Inc. | $36.71B | |
| BNTX Biontech Se | $21.71B | |
| EXEL Exelixis, Inc. | $16.98B | |
| NBIX Neurocrine Biosciences Inc | $16.73B | |
| HALO Halozyme Therapeutics, Inc. | $13.96B | |
| TECH Bio-Techne Corp | $11.43B | |
| KYMR Kymera Therapeutics, Inc. | $11.25B | |
| RGEN Repligen Corp | $11.09B | |
| QGEN Qiagen N.V. | $10.92B | |
| PCVX Vaxcyte, Inc. | $9.51B | |
| IBRX Immunitybio, Inc. | $9.15B | |
| KRYS Krystal Biotech, Inc. | $8.92B | |
| TWST Twist Bioscience Corp | $7.56B | |
| CGON Cg Oncology, Inc. | $6.74B | |
| IMVT Immunovant, Inc. | $6.31B | |
| KOD Kodiak Sciences Inc. | $6.24B | |
| SRRK Scholar Rock Holding Corp | $5.54B | |
| CRSP Crispr Therapeutics Ag | $4.84B | |
| ADPT Adaptive Biotechnologies Corp | $4.28B | |
| RLAY Relay Therapeutics, Inc. | $3.73B | |
| IOVA Iovance Biotherapeutics, Inc. | $3.51B | |
| TARS Tarsus Pharmaceuticals, Inc. | $3.33B | |
| ADMA Adma Biologics, Inc. | $2.85B | |
| BEAM Beam Therapeutics Inc. | $2.73B | |
| VCEL Vericel Corp | $2.65B | |
| COAG Hemab Therapeutics Holdings, Inc. | $2.29B | |
| RXRX Recursion Pharmaceuticals, Inc. | $2.18B | |
| LIFE Atyr Pharma Inc | $2.14B | |
| BCRX Biocryst Pharmaceuticals Inc | $1.95B | |
| MAZE Maze Therapeutics, Inc. | $1.90B | |
| REPL Replimune Group, Inc. | $1.90B | |
| VIR Vir Biotechnology, Inc. | $1.86B | |
| MESO Mesoblast Ltd | $1.83B | |
| NVAX Novavax Inc | $1.78B | |
| ALVO Alvotech | $1.73B | |
| IMCR Immunocore Holdings Plc | $1.60B | |
| TSHA Taysha Gene Therapies, Inc. | $1.33B | |
| VOR Vor Biopharma Inc. | $1.15B | |
| ODTX Odyssey Therapeutics, Inc. | $924M | |
| GLUE Monte Rosa Therapeutics, Inc. | $902M | |
| PRME Prime Medicine, Inc. | $843M | |
| IMTX Immatics N.V. | $829M | |
| MGTX Meiragtx Holdings Plc | $817M | |
| DNA Ginkgo Bioworks Holdings, Inc. | $760M | |
| CGEM Cullinan Therapeutics, Inc. | $728M | |
| SANA Sana Biotechnology, Inc. | $709M | |
| SLDB Solid Biosciences Inc. | $707M | |
| AURA Aura Biosciences, Inc. | $680M | |
| FDMT 4d Molecular Therapeutics, Inc. | $676M | |
| CADL Candel Therapeutics, Inc. | $670M | |
| DBVT Dbv Technologies S.A. | $616M | |
| SRZN Surrozen, Inc./De | $542M | |
| ENTX Entera Bio Ltd. | $518M | |
| SLBT Sl Science Holding Ltd | $513M |
Where DNLI sits on the market map
Denali Therapeutics Inc. (DNLI) stock news
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Denali Therapeutics Inc. (DNLI) stock forecast FAQ
What is the Denali Therapeutics Inc. (DNLI) stock forecast?
Our AI scores Denali Therapeutics Inc. every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.
How accurate are Denali Therapeutics Inc. stock predictions?
For DNLI, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 1.0%, measured on 357 forecast dates between 2022-08-19 and 2026-08-07 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 10.0%, measured on 400 forecast dates between 2022-08-19 and 2026-10-07. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report
How often are Denali Therapeutics Inc. forecasts updated?
Denali Therapeutics Inc. forecasts are refreshed on trading days as the daily model run completes. The forecast on this page was produced on Nov. 6, 2026.
Which companies are Denali Therapeutics Inc.'s industry peers?
60 issuers in our coverage, DNLI included, share the SEC industry code Biological Products, (No Diagnostic Substances). The largest are: Amgen Inc (AMGN), Gilead Sciences, Inc. (GILD), Moderna, Inc. (MRNA), Argenx Se (ARGX), Revolution Medicines, Inc. (RVMD), Biogen Inc. (BIIB).
This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.