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Model output · Signal date 2026-11-05

Taysha Gene Therapies, Inc. (TSHA) Stock Forecast Nov. 5, 2026

Analysis updated on Nov. 5, 2026 (UTC) · Alpha · vs marketSwitch to Total · Nasdaq

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Rating · 90D Unlock rating and forecasts
90-day forecast Sign up free to reveal
30-day forecast Alpha
Rank in coverage of 4891 stocks scored
Rank correlation · 90D -26.0% Spearman, 358 dates
Market Cap $1.33B small-cap · #43 of 60 peers
Summary

Taysha Gene Therapies, Inc. (TSHA) stock forecast summary

Our AI scores Taysha Gene Therapies, Inc. every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.

Taysha Gene Therapies, Inc. is a small-cap company with a market capitalization of $1.33B. It ranks number 43 by market capitalization among the 60 Biological Products, (No Diagnostic Substances) issuers in our coverage with a current forecast.

For TSHA, the Spearman rank correlation between our 90-day forecasts and the returns that followed is -26.0%, measured on 358 forecast dates between 2022-08-18 and 2026-08-07 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is -4.0%, measured on 400 forecast dates between 2022-08-18 and 2026-10-06. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

Expected return relative to the market over the horizon: a positive alpha means the model expects the stock to beat the market, whatever the market does. Ratings: strong buy ≥ +1.9%, buy ≥ +0.2%, sell < -0.9%, strong sell < -1.2% (top 15%, next 20%, middle 30%, next 20%, bottom 15% of the 2026-10-30 signals)

A free account shows the exact forecast, rating and rank of 3 tickers you follow, TSHA included.

Price

TSHA price chart and AI forecast

TSHA
Cross-section · 2026-10-30

How TSHA ranks among 4891 stocks

90D Alpha forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).

Fundamentals · 2026-06-30

Taysha Gene Therapies, Inc. (TSHA) fundamentals

Trailing twelve months. The industry median and the rank (1 = highest) are taken over the Biological Products, (No Diagnostic Substances) peers listed below that report each metric.

Valuation & Market

MetricTSHAIndustry medianRank
Market Cap $1.33B $2.43B 43/60
P/B Ratio 3.44x 4.62x 34/48
EPS $-0.38 – –
Book Value/Share $1.19 – –
Revenue/Share $0.02 – –
FCF/Share $-0.41 – –

Profitability & Margins

MetricTSHAIndustry medianRank
ROE -38.6% -32.3% 25/44
ROA -31.8% -22.2% 29/47
ROIC -34.5% -30.2% 29/52
Operating Margin -2792.3% -35.4% 35/41
Net Margin -2728.0% -34.5% 32/36
EBT Margin -2792.3% -45.6% 37/43
Tax Rate 0.0% – –

Financial Health

MetricTSHAIndustry medianRank
Current Ratio 17.76x 5.23x 4/59
D/E Ratio 0.21x 0.39x 37/52
Financial Leverage 1.21x 1.40x 36/51
Interest Coverage -32.8x -20.2x 20/36
Working Capital $435M $440M 30/58

Cash Flow

MetricTSHAIndustry medianRank
Operating Cash Flow -$132M -$141M 27/56
Free Cash Flow -$133M -$127M 26/49
Capital Spending -$380K -$6M 8/49
FCF/Sales -2417.0% -6.3% 30/32
CapEx/Sales 7.0% 3.0% 8/32

Operational Efficiency

MetricTSHAIndustry medianRank
Asset Turnover 0.01x 0.38x 32/37
Fixed Assets Turnover 2.3x 3.9x 26/38

Income Statement

MetricTSHAIndustry medianRank
Total Revenue $5M $405M 35/38
Operating Income -$153M -$180M 25/53
Net Income -$150M -$179M 23/47
R&D Expense $123M $207M 41/55

Dividend & Shareholder Information

MetricTSHAIndustry medianRank
Shares Outstanding 326M – –

Balance Sheet Highlights (USD millions)

Total Current Assets$461M98.1% of assets
Cash & Short-term Investments$455M96.8% of assets
Total Liabilities$83M17.7% of assets
Short-term Debt$17M3.6% of assets
Quarterly Financial Reports

TSHA quarterly financials and insider trading

Industry Peers · Biological Products, (No Diagnostic Substances)

Taysha Gene Therapies, Inc. (TSHA) industry peers

Companies classified under the same SEC industry code as Taysha Gene Therapies, Inc. (Biological Products, (No Diagnostic Substances)): 60 common-stock issuers with a forecast this week, one row per issuer, largest first. This is a classification match, not a curated list of competitors.

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Company 90-Day AI Forecast (Alpha) Market Cap P/E Ratio P/B Ratio
TSHA Taysha Gene Therapies, Inc. $1.33B – 3.4x
AMGN Amgen Inc $248.84B 26.7x 17.3x
GILD Gilead Sciences, Inc. $207.84B – 15.9x
MRNA Moderna, Inc. $96.40B – 14.3x
ARGX Argenx Se $55.37B 23.5x –
RVMD Revolution Medicines, Inc. $38.08B – 15.9x
BIIB Biogen Inc. $36.06B 105.1x 1.9x
BNTX Biontech Se $21.71B 2.2x –
EXEL Exelixis, Inc. $16.77B 24.7x 9.1x
NBIX Neurocrine Biosciences Inc $16.24B 23.4x 4.2x
HALO Halozyme Therapeutics, Inc. $13.96B 24.9x –
TECH Bio-Techne Corp $11.41B 62.6x 5.4x
QGEN Qiagen N.V. $11.03B 36.1x 2.9x
KYMR Kymera Therapeutics, Inc. $10.94B – 6.8x
RGEN Repligen Corp $10.77B – 5.2x
PCVX Vaxcyte, Inc. $9.21B – 3.7x
KRYS Krystal Biotech, Inc. $8.90B 40.8x 6.2x
IBRX Immunitybio, Inc. $8.49B – –
TWST Twist Bioscience Corp $7.56B – 17.0x
IMVT Immunovant, Inc. $5.86B – 8.0x
CGON Cg Oncology, Inc. $5.74B – 5.6x
KOD Kodiak Sciences Inc. $5.72B – 93.6x
SRRK Scholar Rock Holding Corp $5.54B – 21.8x
CRSP Crispr Therapeutics Ag $4.70B – 2.9x
ADPT Adaptive Biotechnologies Corp $4.28B – 24.3x
RLAY Relay Therapeutics, Inc. $3.73B – 4.6x
IOVA Iovance Biotherapeutics, Inc. $3.51B – 4.3x
TARS Tarsus Pharmaceuticals, Inc. $3.33B – 32.0x
DNLI Denali Therapeutics Inc. $3.15B – 3.4x
ADMA Adma Biologics, Inc. $2.96B 19.7x 6.8x
BEAM Beam Therapeutics Inc. $2.67B 369.6x 2.8x
RXRX Recursion Pharmaceuticals, Inc. $2.18B – 2.4x
COAG Hemab Therapeutics Holdings, Inc. $2.13B – 4.7x
VCEL Vericel Corp $2.10B 83.9x 5.5x
LIFE Atyr Pharma Inc $2.08B – 42.7x
BCRX Biocryst Pharmaceuticals Inc $1.95B – –
REPL Replimune Group, Inc. $1.90B – 9.3x
VIR Vir Biotechnology, Inc. $1.86B – 2.1x
MAZE Maze Therapeutics, Inc. $1.81B – 4.0x
MESO Mesoblast Ltd $1.81B – –
ALVO Alvotech $1.62B – –
NVAX Novavax Inc $1.61B 108.7x –
IMCR Immunocore Holdings Plc $1.46B – 3.5x
VOR Vor Biopharma Inc. $1.15B – –
CGEM Cullinan Therapeutics, Inc. $1.01B – 3.1x
ODTX Odyssey Therapeutics, Inc. $907M – 2.4x
GLUE Monte Rosa Therapeutics, Inc. $874M – 1.8x
IMTX Immatics N.V. $829M – –
MGTX Meiragtx Holdings Plc $817M 11.1x 3.8x
PRME Prime Medicine, Inc. $807M – 20.3x
SANA Sana Biotechnology, Inc. $700M – 3.9x
SLBT Sl Science Holding Ltd $679M – –
DNA Ginkgo Bioworks Holdings, Inc. $671M – 1.6x
SLDB Solid Biosciences Inc. $663M – 1.9x
AURA Aura Biosciences, Inc. $657M – 2.1x
FDMT 4d Molecular Therapeutics, Inc. $621M – 1.5x
DBVT Dbv Technologies S.A. $616M – 3.7x
CADL Candel Therapeutics, Inc. $615M – 4.9x
VALN Valneva Se $551M – –
ENTX Entera Bio Ltd. $518M 9.1x 71.3x

Where TSHA sits on the market map

Life Sciences · Biological Products, (No Diagnostic Substances)
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News

Taysha Gene Therapies, Inc. (TSHA) stock news

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FAQ

Taysha Gene Therapies, Inc. (TSHA) stock forecast FAQ

What is the Taysha Gene Therapies, Inc. (TSHA) stock forecast?

Our AI scores Taysha Gene Therapies, Inc. every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.

How accurate are Taysha Gene Therapies, Inc. stock predictions?

For TSHA, the Spearman rank correlation between our 90-day forecasts and the returns that followed is -26.0%, measured on 358 forecast dates between 2022-08-18 and 2026-08-07 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is -4.0%, measured on 400 forecast dates between 2022-08-18 and 2026-10-06. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

How often are Taysha Gene Therapies, Inc. forecasts updated?

Taysha Gene Therapies, Inc. forecasts are refreshed on trading days as the daily model run completes. The forecast on this page was produced on Nov. 5, 2026.

Which companies are Taysha Gene Therapies, Inc.'s industry peers?

60 issuers in our coverage, TSHA included, share the SEC industry code Biological Products, (No Diagnostic Substances). The largest are: Amgen Inc (AMGN), Gilead Sciences, Inc. (GILD), Moderna, Inc. (MRNA), Argenx Se (ARGX), Revolution Medicines, Inc. (RVMD), Biogen Inc. (BIIB).

This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.