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Stock comparison · Signal date 2026-11-11

DNTH vs IONS: stock comparison and AI forecast

Dianthus Therapeutics, Inc. /De/ (DNTH) and Ionis Pharmaceuticals Inc (IONS) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

Share
Nasdaq · Pharmaceutical Preparations

DNTH Dianthus Therapeutics, Inc. /De/

Price
$88.81 +3.1% · 6M
Market Cap
$4.97B
P/E Ratio
–
Size
mid-cap
AI Forecast
Full analysis →
Nasdaq · Pharmaceutical Preparations

IONS Ionis Pharmaceuticals Inc

Price
$31.00 -58.9% · 6M
Market Cap
$5.15B
P/E Ratio
–
Size
mid-cap
AI Forecast
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

6M · 2026-05-12 → 2026-11-10

Six-month price performance

Closing prices rebased to 100 at the start of the window.

5075100125
DNTH +3.1% IONS -58.9%
DNTH · IONS

Key facts

  • DNTH and IONS have similar market capitalizations ($4.97B and $5.15B).
  • Over the last six months DNTH returned +3.1% and IONS -58.9%.
  • IONS turns -155.6% of its revenue into net income, against -17469.7% for DNTH.
  • IONS carries 6.40 times debt per unit of equity, against 0.03 times for DNTH.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricDNTHIONS
Market Cap$4.97B$5.15B
P/B Ratio4.00x13.09x
EPS$-4.06$-2.93
Book Value/Share$22.19$2.37
Revenue/Share–$2.11
FCF/Share–$-3.71

Profitability & Margins

MetricDNTHIONS
ROE-16.3%-138.8%
ROA-15.8%-18.8%
ROIC-18.9%-22.8%
Gross Margin–95.2%
Operating Margin-20400.0%-160.8%
Net Margin-17469.7%-155.6%
EBT Margin-20400.0%-154.8%
Tax Rate–-0.5%

Financial Health

MetricDNTHIONS
Current Ratio30.02x5.43x
Quick Ratio–5.36x
D/E Ratio0.03x6.40x
Financial Leverage1.03x7.40x
Interest Coverage–-28.2x
Working Capital$828M$1.93B

Cash Flow

MetricDNTHIONS
Operating Cash Flow-$175M-$544M
Free Cash Flow–-$616M
Capital Spending–-$72M
FCF/Sales–-175.4%
CapEx/Sales–20.4%

Operational Efficiency

MetricDNTHIONS
Asset Turnover–0.12x
Inventory Turnover–0.6x
Fixed Assets Turnover–2.2x
Days Inventory–614 days
Payables Period–582 days

Income Statement

MetricDNTHIONS
Total Revenue–$351M
Operating Income-$236M-$565M
Net Income-$202M-$547M
R&D Expense$189M–
SG&A Expense–$585M
Cost of Goods Sold–$17M

Dividend & Shareholder Information

MetricDNTHIONS
Shares Outstanding56M166M
FAQ

DNTH vs IONS: stock comparison and AI forecast

Which is bigger, DNTH or IONS?

DNTH and IONS have similar market capitalizations ($4.97B and $5.15B).

Which stock performed better over the last six months, DNTH or IONS?

Over the last six months DNTH returned +3.1% and IONS -58.9%.

Which one does Intratio's AI model rank higher, DNTH or IONS?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

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This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.