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Stock comparison · Signal date 2026-11-10

IONS vs TVTX: stock comparison and AI forecast

Ionis Pharmaceuticals Inc (IONS) and Travere Therapeutics, Inc. (TVTX) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

Share
Nasdaq · Pharmaceutical Preparations

IONS Ionis Pharmaceuticals Inc

Price
$31.00 -58.9% · 6M
Market Cap
$5.15B
P/E Ratio
–
Size
mid-cap
AI Forecast
Full analysis →
Nasdaq · Pharmaceutical Preparations

TVTX Travere Therapeutics, Inc.

Price
$51.63 +18.7% · 6M
Market Cap
$4.62B
P/E Ratio
–
Size
mid-cap
AI Forecast
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

6M · 2026-05-11 → 2026-11-10

Six-month price performance

Closing prices rebased to 100 at the start of the window.

6090120150
IONS -58.9% TVTX +18.7%
IONS · TVTX

Key facts

  • IONS is 1.1 times larger than TVTX by market capitalization ($5.15B against $4.62B).
  • Over the last six months TVTX returned +18.7% and IONS -58.9%.
  • TVTX turns -18.7% of its revenue into net income, against -155.6% for IONS.
  • TVTX carries 36.56 times debt per unit of equity, against 6.40 times for IONS.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricIONSTVTX
Market Cap$5.15B$4.62B
P/B Ratio13.09x204.62x
EPS$-2.93$-1.12
Book Value/Share$2.37$0.25
Revenue/Share$2.11$7.27
FCF/Share$-3.71–

Profitability & Margins

MetricIONSTVTX
ROE-138.8%-538.0%
ROA-18.8%-14.3%
ROIC-22.8%-20.9%
Gross Margin95.2%98.5%
Operating Margin-160.8%-20.5%
Net Margin-155.6%-18.7%
EBT Margin-154.8%-24.5%
Tax Rate-0.5%3.3%

Financial Health

MetricIONSTVTX
Current Ratio5.43x3.00x
Quick Ratio5.36x2.80x
D/E Ratio6.40x36.56x
Financial Leverage7.40x37.56x
Interest Coverage-28.2x-3.7x
Working Capital$1.93B$423M

Cash Flow

MetricIONSTVTX
Operating Cash Flow-$544M$177M
Free Cash Flow-$616M–
Capital Spending-$72M–
FCF/Sales-175.4%–
CapEx/Sales20.4%–

Operational Efficiency

MetricIONSTVTX
Asset Turnover0.12x0.77x
Receivables Turnover–6.0x
Inventory Turnover0.6x0.2x
Fixed Assets Turnover2.2x239.0x
Days Sales Outstanding–60 days
Days Inventory614 days1675 days
Payables Period582 days584 days
Cash Conversion Cycle–1151 days

Income Statement

MetricIONSTVTX
Total Revenue$351M$651M
Operating Income-$565M-$134M
Net Income-$547M-$122M
R&D Expense–$246M
SG&A Expense$585M$376M
Cost of Goods Sold$17M$10M

Dividend & Shareholder Information

MetricIONSTVTX
Shares Outstanding166M90M
FAQ

IONS vs TVTX: stock comparison and AI forecast

Which is bigger, IONS or TVTX?

IONS is 1.1 times larger than TVTX by market capitalization ($5.15B against $4.62B).

Which stock performed better over the last six months, IONS or TVTX?

Over the last six months TVTX returned +18.7% and IONS -58.9%.

Which one does Intratio's AI model rank higher, IONS or TVTX?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

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This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.