Intratio
Loading...
Skip to main content
Stock comparison · Signal date 2026-11-04

HRMY vs SEPN: stock comparison and AI forecast

Harmony Biosciences Holdings, Inc. (HRMY) and Septerna, Inc. (SEPN) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

Share
Nasdaq · Pharmaceutical Preparations

HRMY Harmony Biosciences Holdings, Inc.

Price
$37.91 +16.3% · 6M
Market Cap
$2.16B
P/E Ratio
11.2x
Size
mid-cap
AI Forecast
Full analysis →
Nasdaq · Pharmaceutical Preparations

SEPN Septerna, Inc.

Price
$45.23 +90.4% · 6M
Market Cap
$2.11B
P/E Ratio
–
Size
mid-cap
AI Forecast
NO CURRENT FORECAST
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

6M · 2026-05-04 → 2026-10-30

Six-month price performance

Closing prices rebased to 100 at the start of the window.

90120150180
HRMY +16.3% SEPN +90.4%
HRMY · SEPN

Key facts

  • HRMY and SEPN have similar market capitalizations ($2.16B and $2.11B).
  • Over the last six months SEPN returned +90.4% and HRMY +16.3%.
  • HRMY turns 18.9% of its revenue into net income, against -24.5% for SEPN.
  • SEPN carries 0.47 times debt per unit of equity, against 0.37 times for HRMY.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricHRMYSEPN
Market Cap$2.16B$2.11B
P/E Ratio11.18x–
P/B Ratio2.16x5.46x
EPS$3.31$-0.83
Book Value/Share$17.16$8.29
Revenue/Share$16.48$2.12
FCF/Share–$2.25

Profitability & Margins

MetricHRMYSEPN
ROE18.1%-6.3%
ROA13.2%-4.3%
ROIC20.2%-8.9%
Gross Margin75.4%–
Operating Margin24.0%-44.0%
Net Margin18.9%-24.5%
EBT Margin25.1%-23.2%
Tax Rate24.9%-5.8%

Financial Health

MetricHRMYSEPN
Current Ratio3.48x4.99x
Quick Ratio3.45x–
D/E Ratio0.37x0.47x
Financial Leverage1.37x1.47x
Interest Coverage29.1x–
Working Capital$580M$317M

Cash Flow

MetricHRMYSEPN
Operating Cash Flow$355M$106M
Free Cash Flow–$105M
Capital Spending–-$910K
OCF Growth YoY36.9%–
FCF/Sales–106.3%
CapEx/Sales–0.9%

Operational Efficiency

MetricHRMYSEPN
Asset Turnover0.70x0.17x
Receivables Turnover8.7x8.1x
Inventory Turnover37.1x–
Fixed Assets Turnover–25.4x
Days Sales Outstanding42 days45 days
Days Inventory10 days–
Payables Period34 days–
Cash Conversion Cycle18 days–

Income Statement

MetricHRMYSEPN
Total Revenue$960M$99M
Operating Income$231M-$44M
Net Income$181M-$24M
R&D Expense$221M$121M
SG&A Expense$352M–
Cost of Goods Sold$236M–

Dividend & Shareholder Information

MetricHRMYSEPN
Shares Outstanding58M47M
Net Income Growth0.2%–
EPS Growth10.7%–
FAQ

HRMY vs SEPN: stock comparison and AI forecast

Which is bigger, HRMY or SEPN?

HRMY and SEPN have similar market capitalizations ($2.16B and $2.11B).

Which stock performed better over the last six months, HRMY or SEPN?

Over the last six months SEPN returned +90.4% and HRMY +16.3%.

Which one does Intratio's AI model rank higher, HRMY or SEPN?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

Compare

More comparisons

This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.