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Stock comparison · Signal date 2026-11-04

SDGR vs SEPN: stock comparison and AI forecast

Schrodinger, Inc. (SDGR) and Septerna, Inc. (SEPN) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

Share
Nasdaq · Pharmaceutical Preparations

SDGR Schrodinger, Inc.

Price
$26.19 +103.0% · 6M
Market Cap
$2.03B
P/E Ratio
–
Size
mid-cap
AI Forecast
Full analysis →
Nasdaq · Pharmaceutical Preparations

SEPN Septerna, Inc.

Price
$45.23 +90.4% · 6M
Market Cap
$2.11B
P/E Ratio
–
Size
mid-cap
AI Forecast
NO CURRENT FORECAST
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

6M · 2026-05-04 → 2026-10-30

Six-month price performance

Closing prices rebased to 100 at the start of the window.

120160200240
SDGR +103.0% SEPN +90.4%
SDGR · SEPN

Key facts

  • SDGR and SEPN have similar market capitalizations ($2.03B and $2.11B).
  • Over the last six months SDGR returned +103.0% and SEPN +90.4%.
  • SEPN carries 0.47 times debt per unit of equity, against 0.46 times for SDGR.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricSDGRSEPN
Market Cap$2.03B$2.11B
P/B Ratio3.71x5.46x
EPS$-0.74$-0.83
Book Value/Share$7.33$8.29
Revenue/Share$3.46$2.12
FCF/Share$-1.74$2.25

Profitability & Margins

MetricSDGRSEPN
ROE–-6.3%
ROA–-4.3%
ROIC–-8.9%
Gross Margin56.9%–
Operating Margin-51.8%-44.0%
Net Margin–-24.5%
EBT Margin-17.5%-23.2%
Tax Rate-4.6%-5.8%

Financial Health

MetricSDGRSEPN
Current Ratio2.71x4.99x
D/E Ratio0.46x0.47x
Financial Leverage–1.47x
Working Capital$297M$317M

Cash Flow

MetricSDGRSEPN
Operating Cash Flow-$127M$106M
Free Cash Flow-$130M$105M
Capital Spending-$3M-$910K
OCF Growth YoY-561.4%–
FCF Growth YoY-634.5%–
FCF/Sales-50.3%106.3%
CapEx/Sales1.3%0.9%

Operational Efficiency

MetricSDGRSEPN
Asset Turnover–0.17x
Receivables Turnover12.1x8.1x
Fixed Assets Turnover13.3x25.4x
Days Sales Outstanding30 days45 days
Payables Period34 days–

Income Statement

MetricSDGRSEPN
Total Revenue$259M$99M
Operating Income-$153M-$44M
Net Income–-$24M
R&D Expense$169M$121M
SG&A Expense$207M–
Cost of Goods Sold$112M–

Dividend & Shareholder Information

MetricSDGRSEPN
Shares Outstanding75M47M
FAQ

SDGR vs SEPN: stock comparison and AI forecast

Which is bigger, SDGR or SEPN?

SDGR and SEPN have similar market capitalizations ($2.03B and $2.11B).

Which stock performed better over the last six months, SDGR or SEPN?

Over the last six months SDGR returned +103.0% and SEPN +90.4%.

Which one does Intratio's AI model rank higher, SDGR or SEPN?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

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This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.