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Model output · Signal date 2026-11-06

Krystal Biotech, Inc. (KRYS) Stock Forecast Nov. 6, 2026

Analysis updated on Nov. 6, 2026 (UTC) · Total · absolute moveSwitch to Alpha · Nasdaq

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Rating · 90D Unlock rating and forecasts
90-day forecast Sign up free to reveal
30-day forecast Total
Rank in coverage of 5150 stocks scored
Rank correlation · 90D 13.0% Spearman, 357 dates
Market Cap $8.92B mid-cap · #17 of 60 peers
Summary

Krystal Biotech, Inc. (KRYS) stock forecast summary

Our AI scores Krystal Biotech, Inc. every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.

Krystal Biotech, Inc. is a mid-cap company with a market capitalization of $8.92B. It ranks number 17 by market capitalization among the 60 Biological Products, (No Diagnostic Substances) issuers in our coverage with a current forecast. Its Net Margin of 47.9% is the highest of the 35 peers that report one.

For KRYS, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 13.0%, measured on 357 forecast dates between 2022-08-19 and 2026-08-07 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 2.0%, measured on 400 forecast dates between 2022-08-19 and 2026-10-07. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

Expected absolute price move over the horizon, market included. This is the number a price target is built from. Ratings: strong buy ≥ +6.2%, buy ≥ +4.2%, sell < +2.1%, strong sell < +0.4% (top 15%, next 20%, middle 30%, next 20%, bottom 15% of the 2026-11-06 signals)

A free account shows the exact forecast, rating and rank of 3 tickers you follow, KRYS included.

Price

KRYS price chart and AI forecast

KRYS
Cross-section · 2026-11-06

How KRYS ranks among 5150 stocks

90D Total forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).

Fundamentals · 2026-09-30

Krystal Biotech, Inc. (KRYS) fundamentals

Trailing twelve months. The industry median and the rank (1 = highest) are taken over the Biological Products, (No Diagnostic Substances) peers listed below that report each metric.

Valuation & Market

MetricKRYSIndustry medianRank
Market Cap $8.92B $2.69B 17/60
P/E Ratio 40.89x 25.87x 6/16
P/B Ratio 6.21x 4.79x 20/48
EPS $7.36 – –
Book Value/Share $48.44 – –
Revenue/Share $15.86 – –
FCF/Share $10.46 – –

Profitability & Margins

MetricKRYSIndustry medianRank
ROE 15.7% -30.7% 8/43
ROA 14.2% -21.5% 6/46
ROIC 15.8% -27.5% 10/52
Operating Margin 48.4% -47.8% 1/40
Net Margin 47.9% -31.7% 1/35
EBT Margin 55.1% -47.7% 1/42
Tax Rate 13.0% – –

Financial Health

MetricKRYSIndustry medianRank
Current Ratio 7.89x 5.72x 22/59
Quick Ratio 7.53x 3.47x 4/29
D/E Ratio 0.10x 0.38x 46/51
Financial Leverage 1.10x 1.39x 45/50
Working Capital $980M $440M 15/58

Cash Flow

MetricKRYSIndustry medianRank
Operating Cash Flow $324M -$141M 12/56
Free Cash Flow $310M -$107M 10/49
Capital Spending -$14M -$6M 35/49
OCF Growth YoY 83.8% 30.3% 3/16
FCF Growth YoY 87.3% 40.0% 4/16
FCF/Sales 66.0% -3.6% 2/32
CapEx/Sales 3.0% 3.0% 17/32

Operational Efficiency

MetricKRYSIndustry medianRank
Asset Turnover 0.30x 0.32x 20/37
Receivables Turnover 3.5x 4.5x 17/23
Fixed Assets Turnover 3.1x 4.2x 24/38
Days Sales Outstanding 103 days 82 days 7/23

Income Statement

MetricKRYSIndustry medianRank
Total Revenue $470M $389M 15/38
Operating Income $228M -$157M 10/53
Net Income $225M -$182M 9/46
R&D Expense $60M $201M 48/55
SG&A Expense $156M $290M 18/23

Dividend & Shareholder Information

MetricKRYSIndustry medianRank
Shares Outstanding 30M – –
Net Income Growth 13.2% 13.2% 6/11
EPS Growth 1.7% 20.0% 9/14

Balance Sheet Highlights (USD millions)

Total Current Assets$1.12B70.7% of assets
Cash & Short-term Investments$463M29.2% of assets
Accounts Receivable$133M8.4% of assets
Inventory$51M3.2% of assets
Total Liabilities$150M9.5% of assets
Short-term Debt$135M8.5% of assets
Quarterly Financial Reports

KRYS quarterly financials and insider trading

Industry Peers · Biological Products, (No Diagnostic Substances)

Krystal Biotech, Inc. (KRYS) industry peers

Companies classified under the same SEC industry code as Krystal Biotech, Inc. (Biological Products, (No Diagnostic Substances)): 60 common-stock issuers with a forecast this week, one row per issuer, largest first. This is a classification match, not a curated list of competitors.

Reveal all forecasts · See exact % predictions for all competitors

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Company 90-Day AI Forecast (Total) Market Cap P/E Ratio P/B Ratio
KRYS Krystal Biotech, Inc. $8.92B 40.9x 6.2x
AMGN Amgen Inc $248.92B 26.7x 17.3x
GILD Gilead Sciences, Inc. $207.00B – 15.9x
MRNA Moderna, Inc. $101.48B – 14.8x
ARGX Argenx Se $57.38B 24.3x –
RVMD Revolution Medicines, Inc. $38.08B – 15.9x
BIIB Biogen Inc. $36.71B 107.1x 1.9x
BNTX Biontech Se $21.71B 2.2x –
EXEL Exelixis, Inc. $16.98B 25.0x 9.3x
NBIX Neurocrine Biosciences Inc $16.73B 24.1x 4.3x
HALO Halozyme Therapeutics, Inc. $13.96B 24.9x –
TECH Bio-Techne Corp $11.43B 66.2x 5.3x
KYMR Kymera Therapeutics, Inc. $11.25B – 7.0x
RGEN Repligen Corp $11.09B – 5.3x
QGEN Qiagen N.V. $10.92B 35.7x 2.9x
PCVX Vaxcyte, Inc. $9.51B – 3.8x
IBRX Immunitybio, Inc. $9.15B – –
TWST Twist Bioscience Corp $7.56B – 17.0x
CGON Cg Oncology, Inc. $6.74B – 6.8x
IMVT Immunovant, Inc. $6.31B – 8.6x
KOD Kodiak Sciences Inc. $6.24B – 102.2x
SRRK Scholar Rock Holding Corp $5.54B – 21.8x
CRSP Crispr Therapeutics Ag $4.84B – 2.9x
ADPT Adaptive Biotechnologies Corp $4.28B – 24.3x
RLAY Relay Therapeutics, Inc. $3.73B – 4.6x
IOVA Iovance Biotherapeutics, Inc. $3.51B – 4.3x
TARS Tarsus Pharmaceuticals, Inc. $3.33B – 32.0x
DNLI Denali Therapeutics Inc. $3.21B – 3.5x
ADMA Adma Biologics, Inc. $2.85B 19.0x 6.5x
BEAM Beam Therapeutics Inc. $2.73B 377.3x 2.9x
VCEL Vericel Corp $2.65B 105.7x 6.9x
COAG Hemab Therapeutics Holdings, Inc. $2.29B – 5.0x
RXRX Recursion Pharmaceuticals, Inc. $2.18B – 2.4x
LIFE Atyr Pharma Inc $2.14B – 62.9x
BCRX Biocryst Pharmaceuticals Inc $1.95B – –
MAZE Maze Therapeutics, Inc. $1.90B – 4.2x
REPL Replimune Group, Inc. $1.90B – 9.3x
VIR Vir Biotechnology, Inc. $1.86B – 2.1x
MESO Mesoblast Ltd $1.83B – –
NVAX Novavax Inc $1.78B 119.8x –
ALVO Alvotech $1.73B – –
IMCR Immunocore Holdings Plc $1.60B – 3.8x
TSHA Taysha Gene Therapies, Inc. $1.33B – 3.4x
VOR Vor Biopharma Inc. $1.15B – –
ODTX Odyssey Therapeutics, Inc. $924M – 2.5x
GLUE Monte Rosa Therapeutics, Inc. $902M – 1.8x
PRME Prime Medicine, Inc. $843M – 21.2x
IMTX Immatics N.V. $829M – –
MGTX Meiragtx Holdings Plc $817M 11.1x 3.8x
DNA Ginkgo Bioworks Holdings, Inc. $760M – 1.8x
CGEM Cullinan Therapeutics, Inc. $728M – 2.3x
SANA Sana Biotechnology, Inc. $709M – 3.9x
SLDB Solid Biosciences Inc. $707M – 2.1x
AURA Aura Biosciences, Inc. $680M – 2.2x
FDMT 4d Molecular Therapeutics, Inc. $676M – 1.7x
CADL Candel Therapeutics, Inc. $670M – 5.3x
DBVT Dbv Technologies S.A. $616M – 3.7x
SRZN Surrozen, Inc./De $542M – –
ENTX Entera Bio Ltd. $518M 9.1x 71.3x
SLBT Sl Science Holding Ltd $513M – –

Where KRYS sits on the market map

Life Sciences · Biological Products, (No Diagnostic Substances)
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News

Krystal Biotech, Inc. (KRYS) stock news

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FAQ

Krystal Biotech, Inc. (KRYS) stock forecast FAQ

What is the Krystal Biotech, Inc. (KRYS) stock forecast?

Our AI scores Krystal Biotech, Inc. every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.

How accurate are Krystal Biotech, Inc. stock predictions?

For KRYS, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 13.0%, measured on 357 forecast dates between 2022-08-19 and 2026-08-07 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 2.0%, measured on 400 forecast dates between 2022-08-19 and 2026-10-07. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

How often are Krystal Biotech, Inc. forecasts updated?

Krystal Biotech, Inc. forecasts are refreshed on trading days as the daily model run completes. The forecast on this page was produced on Nov. 6, 2026.

Which companies are Krystal Biotech, Inc.'s industry peers?

60 issuers in our coverage, KRYS included, share the SEC industry code Biological Products, (No Diagnostic Substances). The largest are: Amgen Inc (AMGN), Gilead Sciences, Inc. (GILD), Moderna, Inc. (MRNA), Argenx Se (ARGX), Revolution Medicines, Inc. (RVMD), Biogen Inc. (BIIB).

This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.