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Model output · Signal date 2026-11-10

Protagonist Therapeutics, Inc (PTGX) Stock Forecast Nov. 10, 2026

Analysis updated on Nov. 10, 2026 (UTC) · Total · absolute moveSwitch to Alpha · Nasdaq

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Rating · 90D Unlock rating and forecasts
90-day forecast Sign up free to reveal
30-day forecast Total
Rank in coverage of 4023 stocks scored
Rank correlation · 90D 1.0% Spearman, 358 dates
Market Cap $8.79B mid-cap · #37 of 60 peers
Summary

Protagonist Therapeutics, Inc (PTGX) stock forecast summary

Our AI scores Protagonist Therapeutics, Inc every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.

Protagonist Therapeutics, Inc is a mid-cap company with a market capitalization of $8.79B. It ranks number 37 by market capitalization among the 60 Pharmaceutical Preparations issuers in our coverage with a current forecast. Its Net Margin of 155.8% is the highest of the 35 peers that report one.

For PTGX, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 1.0%, measured on 358 forecast dates between 2022-08-23 and 2026-08-12 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 32.0%, measured on 400 forecast dates between 2022-08-23 and 2026-10-09. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

Expected absolute price move over the horizon, market included. This is the number a price target is built from. Ratings: strong buy ≥ +6.5%, buy ≥ +4.4%, sell < +2.1%, strong sell < +0.6% (top 15%, next 20%, middle 30%, next 20%, bottom 15% of the 2026-11-10 signals)

A free account shows the exact forecast, rating and rank of 3 tickers you follow, PTGX included.

Price

PTGX price chart and AI forecast

PTGX
Cross-section · 2026-11-10

How PTGX ranks among 4023 stocks

90D Total forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).

Fundamentals · 2026-09-30

Protagonist Therapeutics, Inc (PTGX) fundamentals

Trailing twelve months. The industry median and the rank (1 = highest) are taken over the Pharmaceutical Preparations peers listed below that report each metric.

Valuation & Market

MetricPTGXIndustry medianRank
Market Cap $8.79B $12.99B 37/60
P/E Ratio 34.58x 38.02x 19/32
P/B Ratio 8.11x 7.72x 20/42
EPS $3.93 – –
Book Value/Share $16.77 – –
Revenue/Share $3.39 – –
FCF/Share $1.69 – –

Profitability & Margins

MetricPTGXIndustry medianRank
ROE 31.6% 5.3% 8/39
ROA 29.9% 1.9% 5/43
ROIC 29.6% 1.3% 5/44
Operating Margin 147.1% 10.3% 1/38
Net Margin 155.8% 6.3% 1/35
EBT Margin 158.4% 10.3% 1/46
Tax Rate 2.3% – –

Financial Health

MetricPTGXIndustry medianRank
Current Ratio 19.85x 2.46x 6/58
D/E Ratio 0.06x 1.22x 41/47
Financial Leverage 1.06x 2.12x 41/47
Working Capital $1.05B $920M 26/58

Cash Flow

MetricPTGXIndustry medianRank
Operating Cash Flow $110M $198M 33/59
Free Cash Flow $109M $196M 27/50
Capital Spending -$760K -$52M 8/50
OCF Growth YoY 67.9% 3.7% 6/34
FCF Growth YoY 71.3% 0.0% 5/32
FCF/Sales 49.7% 16.9% 2/42
CapEx/Sales 0.3% 2.8% 35/42

Operational Efficiency

MetricPTGXIndustry medianRank
Asset Turnover 0.19x 0.50x 34/39
Fixed Assets Turnover 66.1x 8.1x 12/41

Income Statement

MetricPTGXIndustry medianRank
Total Revenue $220M $2.90B 44/46
Operating Income $323M $88M 20/50
Net Income $342M $51M 19/47
R&D Expense $176M $603M 51/58

Dividend & Shareholder Information

MetricPTGXIndustry medianRank
Shares Outstanding 65M – –
Net Income Growth 645.5% 5.1% 1/23
EPS Growth 182.7% 6.2% 2/24

Balance Sheet Highlights (USD millions)

Total Current Assets$1.10B96.1% of assets
Cash & Short-term Investments$498M43.5% of assets
Total Liabilities$62M5.4% of assets
Short-term Debt$50M4.3% of assets
Quarterly Financial Reports

PTGX quarterly financials and insider trading

Industry Peers · Pharmaceutical Preparations

Protagonist Therapeutics, Inc (PTGX) industry peers

Companies classified under the same SEC industry code as Protagonist Therapeutics, Inc (Pharmaceutical Preparations): 60 common-stock issuers with a forecast this week, one row per issuer, largest first. This is a classification match, not a curated list of competitors.

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Company 90-Day AI Forecast (Total) Market Cap P/E Ratio P/B Ratio
PTGX Protagonist Therapeutics, Inc $8.79B 34.6x 8.1x
LLY Eli Lilly & Co $1.33T 45.8x 135.1x
JNJ Johnson & Johnson $679.13B 42.9x 8.3x
ABBV Abbvie Inc. $518.30B 44.9x –
MRK Merck & Co., Inc. $367.02B 153.4x 8.2x
NVS Novartis Ag $312.35B 9.8x –
AZN Astrazeneca Plc $293.55B 13.7x –
ABT Abbott Laboratories $192.16B 39.1x 3.8x
NVO Novo Nordisk A S $183.89B 3.1x –
PFE Pfizer Inc $166.60B 37.0x 1.9x
VRTX Vertex Pharmaceuticals Inc / Ma $139.62B 35.5x 6.7x
BMY Bristol Myers Squibb Co $127.02B 13.8x 5.4x
SNY Sanofi $118.63B – –
GSK Gsk Plc $103.98B 5.7x –
REGN Regeneron Pharmaceuticals, Inc. $94.71B 20.4x 2.8x
TAK Takeda Pharmaceutical Co Ltd $65.88B 6.4x –
TEVA Teva Pharmaceutical Industries Ltd $50.07B 41.3x 6.3x
ONC Beone Medicines Ltd. $47.44B 1159.3x 8.2x
GMAB Genmab A/S $35.90B 2.2x –
ZTS Zoetis Inc. $34.02B 14.0x 10.3x
RPRX Royalty Pharma Plc $29.45B 48.1x 4.3x
ROIV Roivant Sciences Ltd. $29.38B – 7.3x
INSM Insmed Inc $25.47B – 35.1x
UTHR United Therapeutics Corp $24.98B 22.0x 4.0x
VTRS Viatris Inc $23.53B – –
ALNY Alnylam Pharmaceuticals, Inc. $20.98B 7.4x 5.8x
ASND Ascendis Pharma A/S $17.07B – –
JAZZ Jazz Pharmaceuticals Plc $15.81B 80.4x 3.8x
BBIO Bridgebio Pharma, Inc. $15.18B – –
SMMT Summit Therapeutics Inc. $14.23B – 25.2x
ELAN Elanco Animal Health Inc $13.41B – 2.0x
RDY Dr Reddys Laboratories Ltd $12.56B 16.5x –
BMRN Biomarin Pharmaceutical Inc $11.07B 571.8x 1.8x
TGTX Tg Therapeutics, Inc. $10.06B 91.9x 17.6x
MDGL Madrigal Pharmaceuticals, Inc. $10.00B – 16.0x
SYRE Spyre Therapeutics, Inc. $9.61B – 9.1x
PRAX Praxis Precision Medicines, Inc. $9.30B – 7.4x
CORT Corcept Therapeutics Inc $8.11B 44.9x 9.7x
RYTM Rhythm Pharmaceuticals, Inc. $7.85B – 89.2x
KNSA Kiniksa Pharmaceuticals International, Plc $7.76B 91.5x 10.9x
ALKS Alkermes Plc. $7.75B 44.8x 4.2x
CYTK Cytokinetics Inc $7.67B – –
AXSM Axsome Therapeutics, Inc. $7.02B – 66.6x
ARWR Arrowhead Pharmaceuticals, Inc. $6.96B – 14.9x
ORKA Oruka Therapeutics, Inc. $6.92B – 5.8x
ABVX Abivax S.A. $6.83B – –
AMRX Amneal Pharmaceuticals, Inc. $6.80B 141.9x –
LGND Ligand Pharmaceuticals Inc $6.28B 119.9x 6.5x
BLTE Belite Bio, Inc $6.20B – 8.1x
MIRM Mirum Pharmaceuticals, Inc. $6.05B – –
MANE Veradermics, Inc $6.01B – 7.4x
COGT Cogent Biosciences, Inc. $5.82B – 11.3x
SUPN Supernus Pharmaceuticals, Inc. $5.56B – 5.2x
ERAS Erasca, Inc. $5.46B – 15.1x
PTCT Ptc Therapeutics, Inc. $5.43B – –
EWTX Edgewise Therapeutics, Inc. $5.29B 5.8x 3.2x
IONS Ionis Pharmaceuticals Inc $5.15B – 13.1x
DNTH Dianthus Therapeutics, Inc. /De/ $5.03B – 4.1x
TVTX Travere Therapeutics, Inc. $4.62B – 204.6x
LEGN Legend Biotech Corp $4.49B – –

Where PTGX sits on the market map

Life Sciences · Pharmaceutical Preparations
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News

Protagonist Therapeutics, Inc (PTGX) stock news

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FAQ

Protagonist Therapeutics, Inc (PTGX) stock forecast FAQ

What is the Protagonist Therapeutics, Inc (PTGX) stock forecast?

Our AI scores Protagonist Therapeutics, Inc every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.

How accurate are Protagonist Therapeutics, Inc stock predictions?

For PTGX, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 1.0%, measured on 358 forecast dates between 2022-08-23 and 2026-08-12 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 32.0%, measured on 400 forecast dates between 2022-08-23 and 2026-10-09. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

How often are Protagonist Therapeutics, Inc forecasts updated?

Protagonist Therapeutics, Inc forecasts are refreshed on trading days as the daily model run completes. The forecast on this page was produced on Nov. 10, 2026.

Which companies are Protagonist Therapeutics, Inc's industry peers?

60 issuers in our coverage, PTGX included, share the SEC industry code Pharmaceutical Preparations. The largest are: Eli Lilly & Co (LLY), Johnson & Johnson (JNJ), Abbvie Inc. (ABBV), Merck & Co., Inc. (MRK), Novartis Ag (NVS), Astrazeneca Plc (AZN).

This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.